Reactive Nasal Inflammation: Current Pathophysiological and Therapeutic Approach.

The pathophysiology of processes that underlie the onset and progression of reactive nasal inflammatory conditions is very complex. These include a heterogeneous group of disorders, ranging from seasonal allergic rhinitis to nonallergic, persisting, refractory forms of chronic rhinosinusitis (CRS). About 400 million people worldwide are affected by allergic rhinitis and another 200 million are thought to be affected by nonallergic forms of nasal inflammation including CRS.