巴基斯坦KPK省乙型肝炎患病率

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摘要

巴基斯坦是世界上慢性肝炎和由肝功能衰竭和肝细胞癌引起的死亡率最高的国家之一。在巴基斯坦,大约有1000万到1200万人患有乙肝。世界卫生组织估计,全世界大约有3亿乙肝病毒携带者。这项研究是在白沙瓦开伯尔教学医院进行的。采用酶联免疫吸附试验(ELISA)和免疫层析技术(ICT)对来自不同地区的3977例患者进行HBsAg筛查。在3977例病例中,81例(2.03%)HBV阳性。合并感染仅6例。与HBV相关的常见危险因素为:牙科治疗史占70%,不合格医生治疗史占49%,输血史占43%,小/大手术史占40%,家庭HBV阳性患者占35%,街头理发师剃须32%,糖尿病占16%,纹身占11%,HCV合并感染7.41%,共用毒品注射器具占1.2%,HIV和tb合并感染占0%
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Prevalence of Hepatitis B in KPK Province Pakistan
Pakistan carries one of the world’s highest burdens of chronic hepatitis and mortality due to liver failure and hepatocellular carcinoma. In Pakistan about 10-12 million of the people are suffering from hepatitis B. World Health organization estimates that there are about 300 million of carriers of HBV all over the world. This study is conducted in the Khyber Teaching Hospital Peshawar. A total of 3,977 patients, belonging to different localities were screened for HBsAg by using ELISA (enzyme linked immunosorbent assay) and ICT (immune chromatographic technique). Out of 3,977 cases, 81(2.03%) were positive for HBV. Co-infection was found only in 6 patients. The common risk factors associated with HBV was found such that history of dental treatment was 70%, treatment from unqualified doctor 49%, history of blood transfusion 43%, history of minor/major surgery 40%, HBV positive patients in family 35%, shaving from street barbers 32%, diabetes 16%, tattooing 11%, HCV co- infection 7.41%, sharing of drug injecting equipment’s 1.2%, HIV and T.B co- infection was 0%
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