少年巨大纤维腺瘤与叶状瘤:了解14岁女性的差异:病例报告

Padron S Johnny A
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摘要

纤维腺瘤是年轻女性乳腺最常见的良性纤维上皮病变,约占青春期乳腺实体病变的90%。然而,青少年巨大纤维腺瘤是一种罕见的乳房疾病,发生在18岁以下的女性。由于幼年巨大纤维腺瘤和叶状瘤的特征相似,均具有快速生长的特点,因此当怀疑其中一种病变时,建立两种病理的鉴别诊断是很重要的,以保证采取最合适的治疗态度。一名14岁女性,无家族病史或个人病史,因临床表现为乳房不对称继发于5个月的左乳房进行性生长而就诊。超声引导下的芯针活检报告了巨大的幼年纤维腺瘤。行乳房肿瘤切除术。组织病理学诊断符合左乳幼年型巨大纤维腺瘤。根据我们的病例和参考文献,我们建议早期鉴别诊断,以及准确的诊断,并对青少年巨大纤维腺瘤进行手术治疗。手术策略和技术取决于诊断时的年龄,乳腺和肿瘤的临床和影像学特征,以及患者的意愿。
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Juvenile Giant Fibroadenoma Vs. Phyllodes Tumor: Know the Difference in a 14-Years-Old Woman: Case Report
Fibroadenoma is the most common benign fibroepithelial lesion of the breast in young women, accounting for around 90% of solid lesions of the gland in adolescence. However, juvenile giant fibroadenoma is a rare breast condition that occurs in women under 18 years of age. Due to the similarity of the characteristics of juvenile giant fibroadenoma and phyllodes tumor, both lesions characterized by rapid growth, it is important to establish the differential diagnosis of both pathologies when one of them is suspected, in order to guarantee the most appropriate therapeutic attitude to follow. A 14-year-old woman with no family or personal history of interest, who consulted due to a clinical picture characterized by breast asymmetry secondary to progressive growth of the left breast of 5 months of evolution. An ultrasound-guided core needle biopsy was performed that reported giant juvenile fibroadenoma. Lumpectomy was performed. Histopathological diagnosis compatible with juvenile giant fibroadenoma of the left breast. Based on our case and on the reviewed bibliography, we recommend an early differential diagnosis, as well as an accurate one, and surgical treatment of cases of juvenile giant fibroadenoma. The surgical tactics and technique depend on the age at the time of diagnosis, the clinical and imaging characteristics of the mammary gland and the tumor, as well as the wishes of the patient in question.
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