Didem GÜLCÜ TAŞKIN, Ali Orgun
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摘要

在本研究中,我们旨在通过评价CD的心电图(ECG)评价中的一些心室复极参数来分析心律失常相关疾病因素的危险因素。本研究回顾性地从患者的档案中进行。2018年1月- 2022年11月阿达纳市培训研究医院63例5-18岁诊断为CD的患者和63例健康对照组的心电图评价正在服用任何药物、患有慢性疾病和/或检测结果异常(维生素B12、叶酸、组织转谷氨酰胺酶、抗肌内膜抗体滴度)的患者被排除在研究之外。心电图分析两组心室复极参数(QT间期、QTc间期、QT离散度、QTc离散度、Tp-e间期、Tp-e/QT、Tp-e/QTc)并进行比较。两组间心室复极参数测量结果无统计学差异。从心电图数据中发现,5岁前诊断的患者QTc min值高于8岁后诊断的患者。8岁以后诊断的患者的QTc离散度高于5岁以前诊断的患者。发现心电图QT min、QT max、QT值受病程影响,与病程(大于5年)有显著高相关性。我们发现,在诊断较晚的患者中,QTc离散度更高。这表明心脏受累在晚期诊断的患者中也会增加。
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Çölyak Hastalarında Elektrokardiyografik Değerlendirmenin Önemi
At the present study, study we aimed to analyze the risk factors for cardiac arrhythmias related disease factors by evaluating some ventricular repolarization parameters in the electrocardiographic (ECG) evaluation of CD. The study was conducted retrospectively from the files of the patients. The ECG evaluation of 63 patients aged 5-18 years diagnosis with CD and 63 healthy control group in Adana City Training and Research Hospital, between 01.2018-11.2022. Patients who were taking any drugs, who had a chronic disease and/or abnormal tests (vitamin B12, folate, tissue transglutaminase, anti-endomysium antibody titers) were excluded from the study. The ventricular repolarization parameters (QT interval, QTc interval, QT dispersion, QTc dispersion, Tp-e interval, Tp-e/QT, Tp-e/QTc) analyzed on ECG and compared both groups. The measured ventricular repolarization parameters of the patients and control groups were not statistically different. From the ECG data, it was found that the QTc min value was higher in patients diagnosed before 5 years old than the patients diagnosed after 8 years old. While the QTc dispersion was higher in patients diagnosed after 8 years old than the patients with an age at diagnosed before 5 years old. It was found that the values of QT min, QT max, and QT in the ECG were influenced by the duration of the disease and significantly high related with the disease duration (more than 5 years). We found that QTc dispersion was higher in patients with a later diagnosis. This suggests that cardiac involvement is also increased in patients with a late diagnosis.
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