舍曲林对印尼强迫症的治疗效果(个案研究)

Muhammad Rais Faisal, Hafid Algristian, Nur Azizah AS
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摘要

背景:强迫症(OCD)最初被认为是一种罕见的精神疾病。然而,最近的调查和研究表明,强迫症是最常见的精神障碍之一。印度的研究表明,使用选择性血清素再摄取抑制剂(SSRIs)治疗强迫症比使用三环类药物更可取。本文将讨论舍曲林作为氯丙咪嗪治疗强迫症的替代品。目的:氯丙咪嗪作为强迫症的治疗选择不再包括在印度尼西亚的MIMS指数中。最近的研究表明舍曲林比氯米帕明更受欢迎,本文通过一个案例研究来讨论舍曲林的疗效。方法:本研究对21岁男性患者进行回顾性描述性研究,该患者符合ICD-X强迫症标准,有不良想法和重复锁门、有序整理书籍的行为。该症状从高中毕业(入学前3年)开始出现,从去年开始恶化。舍曲林是一开始开的处方。在接下来的三个月里,患者在每次就诊期间都接受常规监测。结果:常规服用舍曲林2个月后症状明显改善。不良反应耐受良好,如恶心、头痛和心动过速。需要心理治疗来改变患者的执念,并应注意人格障碍的风险,因为这种障碍在年轻时就出现了。结论:舍曲林和心理治疗是印尼强迫症的一线治疗方法。
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Sertraline on Obsessive Compulsive Disorders in Indonesia (A Case Study)
Background: Obsessive-compulsive disorder (OCD) was originally believed to be a rare mental illness. However, recent surveys and research have shown that OCD is one of the most common mental disorders. Research in India showed that the treatment of OCD using SSRIs (selective serotonin reuptake inhibitors) is preferred over the tricyclic group. This paper will discuss sertraline as the alternative to clomipramine for OCD. Objective: Clomipramine as the treatment of choice for OCD is no longer included in the Indonesian MIMS index. Recent research suggests sertraline is preferred over clomipramine, and this paper discusses the efficacy of sertraline through a case study. Methods: This study is a retrospective descriptive study on the case of 21-year-old male met the ICD-X criteria of OCD for having unwanted thoughts and repetitive behavior for locking the door and orderly compiling the books. The symptoms developed since he graduated from high school (three years before admission) and got worse since the last year. Sertraline was prescribed in the first place. The patient was routinely monitored during each visit for the next three months. Results: The symptoms improved significantly after routinely taking sertraline for two months. The adverse effects were well-tolerated, such as nausea, headaches, and tachycardia. Psychotherapy was needed to modify the patient’s obsession and to anticipate the risk of personality disorder should be noticed because the disorder appeared at a young age. Conclusion: Sertraline as well as psychotherapy are worthy of consideration as first-line OCD therapy in Indonesia.
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