肺部疾病诊断软件:云计算环境下的流感和肺结核案例研究

Ria Lestari, Munawar Ahmad, B. Alisjahbana, T. Djatmiko
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引用次数: 11

摘要

本文以流行性感冒和肺结核为研究对象,对肺部疾病诊断软件进行了研究。流感是一种高度传染性的呼吸道感染。在印度尼西亚,许多禽流感(H5N1)病例发生在农村地区,例如2006年在贾瓦巴拉特加鲁特的病例,该病例始于Cikelet县,造成14例感染病例和5例死亡病例,并使加鲁特处于紧急状态,直到2010年。在农村地区发现H5N1需要快速而准确的诊断结果,以便能够立即采取治疗行动。RT-PCR (Reverse-Transcription Polymerase-Chain-Reaction,逆转录聚合酶链式反应)是最准确的检测方法,该方法投资高,通常位于城市地区。另一种诊断工具是快速诊断试验,它是最常用的诊断工具,但由于其灵敏度和特异性较低,结果不准确。就结核病而言,印度尼西亚排在印度和中国之后,是受感染人数最多的国家。症状是慢性咳嗽带血痰,发烧,盗汗和体重减轻。结核病是通过临床标本中结核分枝杆菌的鉴定来诊断的。当不能这样做时,可能的诊断可使用成像x射线或扫描、结核菌素皮肤试验和/或干扰素- γ释放试验(IGRA)进行。结核病诊断的主要问题是难以在实验室培养这种生长缓慢的有机体,可能需要4至12周的血液或痰培养。要求是建立一种第一手诊断工具,使辅助医务人员能够前往农村地区进行流感/结核病诊断。本研究首先介绍了肺部听诊方法,然后对肺部疾病诊断软件进行了分析和初步设计。为了使省/地区/国家内的每个肺健康公共理事会(Balai Besar Kesehatan Paru Masyarakat)和卫生服务办公室(Dinas Kesehatan)作为数据所有者维护自己的数据,并提供数据机密性,然后应用云计算环境。
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The lung diseases diagnosis software: Influenza and Tuberculosis case studies in the cloud computing environment
This research paper describes study of the lung diseases diagnosis software with Influenza and Tuberculosis as the cases study. Influenza is a highly contagious infection of the respiratory tract. In Indonesia, numerous number of Avian-Influenza (H5N1) cases occurred in rural area, such as cases in Garut, Jawa Barat in 2006 which started in Cikelet district causing 14 infected-cases and 5 death-cases and has put Garut in an emergency situation until 2010. The H5N1 detection in rural area requires fast yet accurate diagnosis result to enable immediate curative actions. The most accurate result is provided by RT-PCR (Reverse-Transcription Polymerase-Chain-Reaction), which is high investment, and usually locates in urban area. Another diagnostic tool, rapid diagnostic test, is most common tool but gives inaccurate result because of its low sensitivity and specificity. In case of Tuberculosis, Indonesia ranks number 3, after India and China, as a country with most number of infected-people. Symptoms are chronic-cough with blood-tinged-sputum, fever, night-sweats and weight-loss. Tuberculosis is diagnosed by identifying Mycobacterium-tuberculosis organism in clinical sample. When this is not possible, probable diagnosis may be made using imaging X-rays or scans, tuberculin skin test and/or Interferon-Gamma-Release-Assay (IGRA). The main problem with tuberculosis diagnosis is difficulty in culturing this slow-growing organism in laboratory, which may take 4 to 12 weeks for blood or sputum-culture. The requirement is to create a first-hand diagnostic tool which allows paramedic mobility to rural areas for Influenza/Tuberculosis diagnostic purposes. The study first introduces lung auscultation method, then analysis and preliminary design of lung diseases diagnosis software. To enable each Lung Health for Public Council (Balai Besar Kesehatan Paru Masyarakat) and Health Service Office (Dinas Kesehatan) within province/region/country as data owner to maintain its own data, and to provide the data confidentiality as well, the cloud computing environment is then applied.
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