治疗青光眼的小梁切除术新技术

S. Petrov, E. A. Suleiman
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摘要

目的。目的:探讨一种改良的鼻窦小梁切除术治疗原发性开角型青光眼的新技术,旨在减少瘢痕形成,改善和延长房水沿新形成的通道流出。方法。在手术过程中,形成浅层和深层巩膜瓣。小梁切除术后,深层皮瓣的外侧边缘向外翻转,相互叠加,形成一个滚轮,其侧面有“凹槽”,用于房水的流出。手术患者52例(52眼),年龄43 ~ 84岁,平均年龄63.4±1.49岁。其中,39例患者被诊断为晚期和远晚期POAG, 13例POAG患者有既往激光和手术治疗史。患者被分为两组:第一组(主要)- 25例患者(25眼)接受改良的鼻窦小梁切除术,包括房水流出形成沟槽;第二组(对照组)- 27例患者(27眼)接受标准的鼻窦小梁切除术。随访时间长达24个月。采用标准的检查方法(粘度法、眼压法、计算机视野法、张力法等)。术后早期进行眼前段光学相干断层扫描,然后进行超声生物显微镜检查。结果。术后1个月,两组平均眼压水平相当且保持在较低水平:1 - 16.7±0.6 mm Hg, 2 - 17.1±0.7 mm Hg。术后1年后,两组IOP均恢复正常。到24个月时,84%的IOP恢复正常,包括药物补偿的患者- 96%。在对照组中,降压成功率为74%,包括药物治疗方案补偿的患者- 88.8%。结论。新发展的鼻窦小梁切除术手术治疗青光眼达到长期的降压效果。
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A new trabeculectomy technique for the treatment of glaucoma
   PURPOSE. To develop a new modified technique of sinus trabeculectomy for the surgical treatment of primary open-angle glaucoma (POAG) aimed at reducing scarring and improving and prolonging the outflow of aqueous humor along newly formed pathways.   METHODS. In the course of the surgery, superficial and deep scleral flaps were formed. After trabeculectomy, the lateral edges of the deep flap were turned inside out and superimposed on each other, forming a roller with "grooves" on its sides used for the outflow of aque-ous humor. The operation was performed in 52 patients (52 eyes) aged 43 to 84 years old (mean age 63.4 ± 1.49 years). Of these, 39 patients were diagnosed with POAG at advanced and far advanced stages, and 13 patients with POAG and a history of previous laser and surgical interventions. The patients were divided into groups: group 1 (main) — 25 patients (25 eyes) who underwent the modified sinus trabeculectomy involving the formation of grooves for the outflow of aqueous humor, and group 2 (controls) — 27 patients (27 eyes) who underwent standard sinus trabeculectomy. The follow-up lasted up to 24 months. Standard methods of examination were used (visometry, tonometry, computer perimetry, tonography, etc.). Optical coherence tomography of the anterior segment of the eye was performed in the early postoperative period, followed by ultrasound biomicroscopy.   RESULTS. One month after surgery, the average level of intraocular pressure was comparable and remained low in all groups: 1 — 16.7 ± 0.6 mm Hg, 2 — 17.1 ± 0.7 mm Hg. After one year post surgery, IOP remained normalized in both groups. By 24 months, IOP normalization was preserved in 84 %, and including patients compensated on medication — 96 %. In the control group, the hypotensive success rate was 74 %, and including patients compensated on a medication regimen — 88.8 %.   CONCLUSION. The newly developed sinus trabeculectomy technique for the surgical treatment of glaucoma achieves a prolonged hypotensive effect.
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