药理学和药物治疗的偏见:利血平作为抑郁症实验研究的模型。

H J Bein
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引用次数: 3

摘要

选择利血平作为二十年来抑郁症研究中实际使用的唯一模型物质并不仅仅是出于理性考虑:假设的概念、快速实现实验研究目标的前景以及这种“天然”药物的异国起源的魅力都做出了重大贡献。
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Prejudices in pharmacology and pharmacotherapy: reserpine as a model for experimental research in depression.
The choice of reserpine as practically the sole model substance used in research in depression over two decades was not dictated by rational considerations alone: hypothetical notions, prospects of the rapid realization of experimental research aims and the fascination of the exotic origin of this "natural" drug made a significant contribution.
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