{"title":"胰岛素自身免疫综合征(平田病):1例新发糖尿病白人患者","authors":"M. Sudano, F. Turchi, P. Sossai","doi":"10.5923/J.CMD.20120205.02","DOIUrl":null,"url":null,"abstract":"An unusual cause of spontaneous hypoglycemia is Insulin Autoimmune Syndrome (or Hirata Disease), characterized by high levels of insulinemia and circulating autoantibodies to insulin in subjects without prior insulin administration. In Western Countries less than 70 cases have been published so far. Here we report a case where IAS was the prodromical stage of new onset type 1 diabetes. HLA typing in IAS was rarely reported in Western cases, here we also discuss the peculiar HLA pattern of our patient.","PeriodicalId":101352,"journal":{"name":"Clinical medicine and diagnostics","volume":"4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Insulin Autoimmune Syndrome (Hirata Disease): Case Report in a Caucasian Patient with New-Onset Diabetes\",\"authors\":\"M. Sudano, F. Turchi, P. Sossai\",\"doi\":\"10.5923/J.CMD.20120205.02\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"An unusual cause of spontaneous hypoglycemia is Insulin Autoimmune Syndrome (or Hirata Disease), characterized by high levels of insulinemia and circulating autoantibodies to insulin in subjects without prior insulin administration. In Western Countries less than 70 cases have been published so far. Here we report a case where IAS was the prodromical stage of new onset type 1 diabetes. HLA typing in IAS was rarely reported in Western cases, here we also discuss the peculiar HLA pattern of our patient.\",\"PeriodicalId\":101352,\"journal\":{\"name\":\"Clinical medicine and diagnostics\",\"volume\":\"4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical medicine and diagnostics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5923/J.CMD.20120205.02\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical medicine and diagnostics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5923/J.CMD.20120205.02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Insulin Autoimmune Syndrome (Hirata Disease): Case Report in a Caucasian Patient with New-Onset Diabetes
An unusual cause of spontaneous hypoglycemia is Insulin Autoimmune Syndrome (or Hirata Disease), characterized by high levels of insulinemia and circulating autoantibodies to insulin in subjects without prior insulin administration. In Western Countries less than 70 cases have been published so far. Here we report a case where IAS was the prodromical stage of new onset type 1 diabetes. HLA typing in IAS was rarely reported in Western cases, here we also discuss the peculiar HLA pattern of our patient.
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