Chronic Recurrent Multifocal Osteomyelitis Involving The Skull

We report a rare case of chronic recurrent multifocal osteomyelitis of the skull. A 21-year-old man presented with headache and fever. Skull radiography revealed hypertransradiancy with multiple round marginal irregular osteoclasia. Computed tomography (CT) scan showed a thick skull, heterogeneous diploe, and a lot of hardened macular shadow; however, the underlying brain tissue was normal. Tc-methylene diphosphonate (MDP) bone scintigraphy showed high activity in the skull and tibia. During surgery for this bone lesion, inflammatory changes were noted; however, they were not neoplastic.Chronic recurrent multifocal osteomyelitis of the skull bone is extremely rare and we could find only 1 reported case in the literature.