一例罕见的急性心肌炎

Károly Péter Sárvári, S. Zolyomi, G. Ágoston, G. Terhes, H. Gavallér, T. Forster, A. Varga, E. Urbán
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引用次数: 1

摘要

急性心肌炎是一种影响广泛的炎症性疾病,主要由病毒引起。eb病毒很少引起急性心肌炎。一名19岁健康男子因突发性上腹部及胸痛入院。实验室检查怀疑急性心肌梗死,但MRI和超声心动图显示心肌水肿是炎症的一部分。在其既往病史中,没有毒物接触和出国旅行的记录。急性心肌炎最常见的病毒PCR检测结果均为阴性,但EBV抗vca IgM阳性,可检测到后来的血清转化,同时,典型的单核细胞增多症证实了EBV的病原作用。在β受体阻滞剂和ace抑制剂治疗的基础上,大剂量非甾体抗炎药治疗3周后,对照MRI水肿消失,但心电图仍呈阳性,一般情况满意出院。在6个月的对照MRI中,没有任何心肌炎的迹象,也没有收缩射血分数下降,心电图也转为阴性。
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A Rare Case of Acute Myocarditis
Acute myocarditis is an inflammatory disease with a quite broad range of consequences caused mostly by viruses. Epstein-Barr virus (EBV) rarely causes acute myocarditis. A 19-year-old healthy man with sudden epigastrial and chest pain was admitted to hospital. Laboratory investigations suspected acute myocardial infarct, but MRI and echocardiography showed myocardial oedema as part of inflammation. In his past medical history, toxic exposition and travelling abroad could not be recorded. PCR investigations of the most common viruses causing acute myocarditis gave negative results, but positive EBV anti-VCA IgM, and later sero conversion could be detected and simultaneously, a typical mononucleosis proved the aetiological role of EBV. After a 3-week-long high dose NSAID therapy on the basis of beta-blocker and ACE-inhibitor therapy, on control MRI oedema disappeared, but electrocardiography was still positive, the patient with satisfying general status was discharged home. On the 6 month control MRI, neither any signs of myocarditis, nor decreased systolic ejection fraction were noted, and also ECG turned negative.
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