类风湿性关节炎的生物治疗:主要已批准单克隆抗体的综述

Worldwide Medicine Pub Date : 1900-01-01 DOI:10.5455/ww.53482

Josemar Faustino, Douglas Oliveira, T. Fernandes, P. Simioni

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摘要

类风湿关节炎(RA)是一种慢性自身免疫性炎症疾病，在其整个发展过程中具有很高的破坏性。疾病的演变产生了巨大的社会和经济代价。1-3这是一种病因不明的多因素全身性疾病，主要影响关节，随着关节破坏和畸形而发展，常导致丧失行为能力。4、5文摘

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Biological treatment for rheumatoid arthritis: a review of the main approved monoclonal antibodies

Introduction Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that has a high destructive potential throughout its progression. The disease evolution generates significant social and economic costs. 1–3 This is a multifactorial and systemic disease of unknown etiology, which can mainly affect the joints, evolving with joint destruction and deformity, often becoming incapacitating. 4,5 Abstract

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Worldwide Medicine

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