利用磁干扰法无创测量血流

C. T. Phua, Gaelle Lissorgues
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引用次数: 12

摘要

目前的激光多普勒血流传感方法需要与皮肤进行光学接触,往往体积庞大,并且对体液(如血液、汗水)和环境污染物(如泥浆、水)的性能也很主观。本文提出了一种通过测量血液流经局部磁场所产生的磁干扰来无创采集血流的新方法。该系统采用基于GMR的磁传感器和半径为3毫米的磁铁,放置在主要血管上。磁体产生的磁场既作为传感器的偏置场,又作为血流干扰的均匀磁通量。因此,该系统结构紧凑,可在室温下工作,并能通过衣服进行感应。利用闭塞后反应性充血试验对磁法和光法获得的信号进行比较,发现6个不同健康受试者的测量结果误差小于5%,表明磁法测量血流的成功使用。
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Non-invasive measurement of blood flow using magnetic disturbance method
Current laser Doppler method of blood flow sensing requires optical contact to the skin, tend to be bulky and have performance subjective to body fluids (e.g. blood, perspiration) and environmental contaminants (e.g. mud, water). This paper proposes a novel method of noninvasive acquisition of blood flow by measuring the magnetic disturbance created due to blood flowing through a localized magnetic field. The proposed system employs a GMR based magnetic sensor and magnet of 3 mm radius, placed on a major blood vessel. The magnetic field generated by the magnet acts both as the biasing field for the sensor and also the uniform magnetic flux for blood flow disturbance. As such, the system is compact, operates at room temperature and is able to sense through clothing. The signal acquired from the magnetic and optical methods are compared using the post-occlusive reactive hyperaemia test, where measurement results on 6 different healthy subjects are found to have error of less than 5%, showing the successful use of the magnetic method to measure blood flow.
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