Katuk叶提取物(Sauropus Androgynus)对母乳生产的影响

Darmawati Darmawati, Hajjul Kamil, R. Rosmawati, M. Rizkia, Nova Fajri
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摘要

母乳(ASI)是一种富含各种生物活性因子的营养来源。其独特的成分,母乳是需要为婴儿的最佳生长和发育做准备。katuk (Auropus Androgynus)叶子上的植物传统上被印度尼西亚人用来增加母乳产量。卡图克叶的含量几乎含有7%的蛋白质和高达19%的粗纤维。这些叶子富含维生素K和维生素A (β -胡萝卜素)、B和c。它们含有的矿物质是钙。本研究的目的是确定鹿角叶提取物对实验动物(家兔)泌乳的潜力。从亚齐Besar区(Samahani, Indrapuri和Seulimun村)获得的Katuk叶。他们在化学系实验室(FMIPA USK)进行了植物化学过程,在USK兽医学院药理学实验室进行了提取过程。实验动物样本均为刚分娩的家兔,分为3组,对照组6只,15 mg剂量组6只,30 mg剂量组6只。通过测定第1、7、14天家兔的乳汁进行评价。使用广义线性模型检验(Post Hoc Bonferroni Repeated ANOVA)的研究结果显示,三组的p值为0.001。由此可见,各组间母乳量各指标均有差异,差异值(CI 95%)分别为第1天0.04(0.002 ~ 0.084)、第7天0.05(0.020 ~ 0.090)、第14天0.12(0.065 ~ 0.175)。这项研究的建议是,可以对katukuk叶提取物的潜力进行进一步的研究,以进入临床试验阶段,使其适合于人类使用,特别是产后妇女,以提高母乳产量。
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The Effectiveness of Katuk Leaf Extract (Sauropus Androgynus) on Breastmilk Production
Breast Milk (ASI) is a source of nutrients that are loaded with various bioactive factors. Its unique composition, breast milk is needed to prepare for optimal growth and development for babies. Plants on the leaves of katuk (Auropus Androgynus) are traditionally used by Indonesian people to increase breast milk production. The content of the katuk leaves contains almost 7% protein and up to 19% crude fiber. These leaves are rich in vitamin K and pro-vitamin A (beta-carotene), B, and C. The minerals they contain are calcium. The purpose of this study was to identify the potential of katuk leaf extract on breast milk production in experimental animals (rabbits). Katuk leaves were obtained from Aceh Besar District (Samahani, Indrapuri and Seulimun Village). They carried out the phytochemical process in the Department of Chemistry’s laboratory, FMIPA USK and the extraction process in the pharmacology laboratory of the Faculty of Veterinary Medicine, USK. The experimental animal samples, which were rabbits that had just given birth, were divided into three groups, which were 6 rabbits in the control group, 6 rabbits in the 15 mg dose group and 6 rabbits in the 30 mg dose group. An evaluation was carried out by measuring the breastmilk of rabbits on days 1, 7 and 14. The results of the study using the Generalized Linear Model test (Post Hoc Bonferroni Repeated ANOVA) showed a p-value of .001 for the three groups. It can be concluded that there was a difference in the amount of breast milk between groups in all measurements with the difference value (CI 95%) on the 1st day 0.04 (0.002-0.084), the 7th day 0.05 (0.020-0.090), and the 14th day 0.12 (0.065-0.175). Recommendations from this study are that further research can be carried out regarding the potential of katuk leaf extract to the clinical trial stage so that it is suitable for use in humans, especially postpartum women to increase breast milk productivity.
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