索科托州一家三级医疗机构管理的严重急性营养不良患者的临床概况和治疗结果

K. O. Isezuo, M. Amodu-Sanni, A. Adamu, B. I. Garba, F. Jiya, Tahir Yusuf Bello, M. Ugege, B. Jibrin
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摘要

背景:严重急性营养不良(SAM)影响着全世界2000多万儿童,在非洲地区非常普遍,那里的卫生系统也在应对其他高度流行的传染病和非传染病。世界卫生组织(世卫组织)建议在设施中就风险因素和后续护理标准方面的治疗结果进行更多研究。本研究评估了索科托一家三级医院收治的SAM患者的临床表现和治疗结果。方法:回顾性分析了两年内因SAM入院的6个月至5岁儿童的记录。使用形式表格收集他们的社会人口统计信息、营养不良类型、人体测量特征、堆积细胞体积、并发症、接受的治疗和结果。数据分析采用IBM SPSS version 25。结果:期间收治的1862例患者中,有SAM 159例(8.5%),其中有记录107例。大多数病例是在7月至9月的雨季入院的。男女比例为1.43:1。平均年龄21.0±8.6个月。非水肿性SAM 66例(61.7%),水肿性SAM 41例(38.3%)。水肿性SAM的包细胞体积比非水肿性SAM小,枕额围比非水肿性SAM高(p=0.03)。给予的营养康复饮食包括世卫组织配方奶和医院配制的营养kwash pap。平均体重增加14g/kg/d,死亡率为45.8%,康复率为17%,未参加随访的比例高达70.6%。体重是出院前唯一记录的人体测量数据。结论:SAM患者死亡率高,随访差。管理团队需要通过统一的饮食改善再喂养做法,监测康复的所有人体测量指标,并确保通过适当的转诊在社区对这些患者进行随访。
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Clinical Profile and Treatment Outcome among Patients Managed for Severe Acute Malnutrition in a Tertiary Facility in Sokoto State
Background: Severe acute malnutrition (SAM) affects more than 20 million children worldwide, and it is highly prevalent in the African region where health systems are also coping with other highly prevalent infectious and non-infectious diseases. World Health Organization (WHO) recommends more research in facilities on treatment outcomes in relation to risk factors and standards of follow up care. This study evaluated the clinical profile at presentation and outcome of treatment of SAM among patients admitted into a tertiary hospital in Sokoto Methods: A retrospective review of records of children aged six months to 5 years who were admitted for SAM over a two-year period. A proforma was used to collect the information on their socio-demographics, type of malnutrition, anthropometric characteristics, packed cell volume, complications, therapy received and outcome. Data were analysed using IBM SPSS version 25. Results: Out of the 1862 patients admitted during the period, 159 (8.5%) had SAM, and of these, 107 records were available. Most cases were admitted in the rainy months of July to September. The male to female ratio was 1.43:1. The mean age was 21.0 ± 8.6 months. There were 66 (61.7%) cases of non-oedematous SAM and 41 (38.3%) cases of oedematous SAM. Oedematous SAM had lower pack cell volume and higher occipitofrontal circumference than non-oedematous SAM (p=0.03). Nutritional rehabilitation diet given included WHO formula milk and the hospital prepared nutrient kwash pap. Mean weight gain was 14g/kg/day, mortality was 45.8%, recovery rate 17%, and a large proportion 70.6% did not attend follow up. Weight was the only anthropometry documented subsequently till discharge. Conclusions: There was high mortality and poor follow up among the SAM patients. The managing team needs to improve refeeding practices with uniform diet, monitor all anthropometric indicators of recovery and ensure follow up of these patients in the community by appropriate referral.
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