调控基因表达——RNAi和CRISPR-Cas9技术的桥接

Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies Pub Date : 2019-02-06 DOI:10.5772/intechopen.84229

Aditi Singh

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引用次数: 26

摘要

另一方面，聚集规律间隔短回文重复序列(CRISPR)相关的Cas9/ gRNA系统是源自原核免疫系统的一种独特的靶向基因组修饰技术。近年来的前沿研究和技术进步使CRISPR-Cas9系统成为在真核生物基因组中引入可遗传的、精确的插入和缺失的流行工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies

The clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/ gRNA system on the other hand, is a unique, targeted genome-modification technique derived from prokaryotic immune system. The cutting edge research and technology advancements in recent years have enabled the CRISPR-Cas9 system to become a popular tool for introducing heritable, precised, insertions and deletions in the eukaryotic genome.

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Modulating Gene Expression - Abridging the RNAi and CRISPR-Cas9 Technologies

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