脱髓鞘小鼠模型的相关结构和功能缺陷

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN) Pub Date : 1900-01-01 DOI:10.1364/boda.2023.jtu4b.19

Aniruddha Das, Julie A. Borovicka, Jacob Icardi, Priyanka Agochiya, Shriya Singh, H. Dana

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摘要

同时双光子和三次谐波显微镜记录的小鼠海马喂养铜酮诱导脱髓鞘显示髓磷脂损失的严重程度和减少神经元放电之间的相关性。

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Correlated Structural and Functional Deficits in a Mouse Model of Demyelination

Concurrent two-photon and third-harmonic generation microscopy recordings from the hippocampus of mice fed with cuprizone to induced demyelination showed a correlation between the severity of myelin loss and reduced neuronal firing in the same mice.

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Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)

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