健康个体口腔中寄生菌的风险因素(FKG UI研究)

Audiawati Audiawati, Siti Aliyah Pradono, Febrina Rahmayanti
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摘要

简介:口腔念珠菌病在健康人群和免疫功能低下患者中都很常见,但在印度尼西亚,关于健康人群口腔念珠菌携带者和定植危险因素的出版物几乎没有。目的:分析表面健康的FKG学生口腔内念珠菌菌落类型和数量,探讨口腔内念珠菌的危险因素。材料和方法:采用口腔冲洗技术采集195名受试者的标本,用培养基CHROMagar®和Sabaraoud葡萄糖琼脂进行鉴定。结果与讨论:107例口腔检出念珠菌(54.87%),其中白色念珠菌为优势菌(52.33%)。菌落数为400 CFU/ml者占88例(82.24%),其余为400 CFU/ml者(17.76%)。假丝酵母菌落以单菌落为主(90.65%),其余为多菌落(9.34%)。确定的危险因素包括年龄;性别;激素;O型血;假牙;矫正装置;未受刺激的唾液流量;唾液的pH值;有吸烟、饮酒和清洁口腔的习惯;口腔健康状况。经统计学Pearson卡方检验,危险因素与口腔念珠菌菌落数无显著相关(p0.05)。结论:念珠菌定殖的危险因素不是单一的,而是人口统计学、局地性和全身性等多种危险因素共同作用的结果
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IDENTIFIKASI FAKTOR RISIKO TERJADINYA KOLONISASI SPESIES CANDIDA DI RONGGA MULUT PADA INDIVIDU SEHAT (PENELITIAN PADA MAHASISWA & MAHASISWI FKG UI)
Introduction : Cases of oral candidiasis are commonly found, both in healthy individuals and immunecompromise patients, however publications of Candida carrier in the oral cavity of healthy population and risk factors for colonization in Indonesia are hardly available. Objective : This study was aimed to analyze the type and number of Candida colonies and identify risk factors in the oral cavity of apparenthly health FKG UI students. Material and methods : the specimens were taken from 195 subjects with oral rinse technique for identification using culture medium CHROMagar® and Sabaraoud dextrose agar. Results and discussion : Candida species were found in the 107 subjects oral cavity (54.87%), being Candida albicans was is the predominant species (52.33%). Some 88 subjects (82.24%) was dominant in the number of colonies 400 CFU/ml, while the rest had colony of 400 CFU/ml (17.76%). Candida colony grew dominantly in single colony (90.65%), and the others showed multi-species colonies (9.34%). Risk factors identified included age; gender; hormonal; blood type O; denture; orthodontic appliances; unstimulated salivary flow; pH of saliva; smoking, alcohol and oral cleaning habit; and oral health status. By using a statistical Pearson chi-square test, no  significant relationship was found between risk factors and number of Candida colonies in the oral cavity p0.05. Conclusion : there was no one single risk factor for Candida colonization, but  combination of various risk factors for demographis, local and systemic was observed
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