A. Lukyanov, D. Donskoy, M. Vernezi, M. Mazanko, S. Studennikova
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EXPERIENCE IN DEVELOPING MODELS OF ARTIFICIAL GASTROINTESTINAL TRACTS OF ANIMALS
For „in-vitro“ experimental study of the effect of probiotics on the development of microbiota of poultry and domestic animals, a line of „SHIME“ – like models of artificial gastrointestinal tracts in the form of complexes of miniature bioreactors with microcontroller control and monitoring systems was created. Experience in operating this equipment in an experimental study of the effect of prebiotics on the development of intestinal microbiota has allowed to establish a number of features and limitations, which are brought in this paper. The peculiarities of setting up peristaltic pumps, magnetic mixers and the choice of connecting tube configuration are considered.