{"title":"使用词嵌入的无监督学习从COVID-19药物文献中捕获静态知识","authors":"Tasnim Gharaibeh, E. Doncker","doi":"10.1109/CSCI51800.2020.00081","DOIUrl":null,"url":null,"abstract":"As COVID-19 patients flood hospitals worldwide, physicians are trying to search for effective antiviral therapies to save lives. However, there is currently a lack of proven effective medications against COVID-19. Multiple COVID-19 vaccine trials and treatments are underway, but yet need more time and testing. Furthermore, the SARS-CoV-2 virus that causes COVID-19 replicates poorly in multiple animals, including dogs, pigs, chickens, and ducks, which limits preclinical animal studies. We built an unsupervised deep learning model (CDVec) to produce word-embeddings using word2vec from a corpus of articles selectively focusing on COVID-19 candidate drugs that appeared in the literature to identify promising target drugs that could be used in COVID-19 treatment.","PeriodicalId":336929,"journal":{"name":"2020 International Conference on Computational Science and Computational Intelligence (CSCI)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Unsupervised Learning with Word Embeddings Captures Quiescent Knowledge from COVID-19 Drugs Literature\",\"authors\":\"Tasnim Gharaibeh, E. Doncker\",\"doi\":\"10.1109/CSCI51800.2020.00081\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"As COVID-19 patients flood hospitals worldwide, physicians are trying to search for effective antiviral therapies to save lives. However, there is currently a lack of proven effective medications against COVID-19. Multiple COVID-19 vaccine trials and treatments are underway, but yet need more time and testing. Furthermore, the SARS-CoV-2 virus that causes COVID-19 replicates poorly in multiple animals, including dogs, pigs, chickens, and ducks, which limits preclinical animal studies. We built an unsupervised deep learning model (CDVec) to produce word-embeddings using word2vec from a corpus of articles selectively focusing on COVID-19 candidate drugs that appeared in the literature to identify promising target drugs that could be used in COVID-19 treatment.\",\"PeriodicalId\":336929,\"journal\":{\"name\":\"2020 International Conference on Computational Science and Computational Intelligence (CSCI)\",\"volume\":\"15 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2020 International Conference on Computational Science and Computational Intelligence (CSCI)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/CSCI51800.2020.00081\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2020 International Conference on Computational Science and Computational Intelligence (CSCI)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CSCI51800.2020.00081","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Unsupervised Learning with Word Embeddings Captures Quiescent Knowledge from COVID-19 Drugs Literature
As COVID-19 patients flood hospitals worldwide, physicians are trying to search for effective antiviral therapies to save lives. However, there is currently a lack of proven effective medications against COVID-19. Multiple COVID-19 vaccine trials and treatments are underway, but yet need more time and testing. Furthermore, the SARS-CoV-2 virus that causes COVID-19 replicates poorly in multiple animals, including dogs, pigs, chickens, and ducks, which limits preclinical animal studies. We built an unsupervised deep learning model (CDVec) to produce word-embeddings using word2vec from a corpus of articles selectively focusing on COVID-19 candidate drugs that appeared in the literature to identify promising target drugs that could be used in COVID-19 treatment.