LSTM在蛋白质结构预测中的应用

Lina Yang, Pu Wei, Xichun Li, Yuanyan Tang
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引用次数: 0

摘要

本文讨论了LSTM神经网络在蛋白质结构预测中的应用。主要思想是构造一个LSTM神经网络。预测蛋白质的二级结构是预测其空间结构的基础内容。在本文中,包含进化信息的位置特定评分矩阵(PSSM)与其他特征相关联,以构建一个全新的特征集。选择CB513数据集构建LSTM神经网络,预测序列的二级结构。实验结果表明,该方法有效地提高了预测精度,优于原有的预测方法。本文的思想也适用于其他序列的分析。
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Application Of LSTM In Protein Structure Prediction LINA
In this paper the authors discuss the applications of LSTM Neural Network in Protein Structure Prediction. The main idea is to construct a LSTM neural network. Predicting the secondary structure of a protein is the basis content for predicting its spatial structure. In this article, a position-specific scoring matrices (PSSM) containing evolutionary information is linked to other features to construct a completely new feature set. The CB513 data set is selected to construct LSTM neural networks to predict the secondary structure of the sequence. Experiments have shown that the proposed method effectively improves the prediction accuracy and is better than the previous method. The idea in this paper can also be applied to the analysis of other sequences.
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