优化外科用β射线相机中使用的薄闪烁体的光收集

Craig S. Levin, L. R. MacDonald, M. Tornai, Edward J. Hoffman, J. Park
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引用次数: 27

摘要

作者正在开发一种1- 2cm /sup / area相机,用于成像手术中暴露的组织表面β -放射药物的分布。前端由一个非常薄的连续或分段闪烁体组成,对几百keV的β(正电子或电子)敏感,但对伽马射线不敏感。来自闪烁体的光通过透明光纤输送到光子探测器(PD)。这种方法要求足够数量的闪烁光子从闪烁体通过光纤传输到PD。闪烁体、反射器、表面处理、几何形状、光纤光导和光耦合必须优化。作者在此报告了利用实验测量和计算机模拟优化从< 3mm厚的塑料和CaF/sub 2/(Eu)闪烁体到透明纤维的光收集的努力。作者测量了一个直径1.25 cm,厚度0.5 mm的优化CaF/sub 2/(Eu)磁盘与一个5 cm长的透明光纤束耦合,在PMT光电阴极上平均产生/spl sim/250个光电子,用于/sup 204/Tl β流源(E/sub max/=763 keV)。这对应于足够数量的光电子,用于建议的相机的<1毫米分辨率成像能力。
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OPTIMIZING LIGHT COLLECTION FROM THIN SCINTILLATORS USED IN A BETA-RAY CAMERA FOR SURGICAL USE
The authors are developing a 1-2 cm/sup 2/ area camera for imaging the distribution of beta-emitting radiopharmaceuticals at the surface of tissue exposed during surgery. The front end consists of a very thin continuous or segmented scintillator sensitive to betas (positrons or electrons) of a few hundred keV, yet insensitive to gamma rays. The light from the scintillator is piped through clear fibers to the photon detector (PD). This approach requires that a sufficient number of scintillation photons be transported from the scintillator, through the fibers to the PD. The scintillator, reflector, surface treatments, geometry, fiber light guides, and optical couplings must be optimized. The authors report here on efforts made to optimize the light collection from <3 mm thick plastic and CaF/sub 2/(Eu) scintillators into clear fibers using experimental measurements and computer simulations. The authors measured that with a 1.25 cm diameter, 0.5 mm thick optimized CaF/sub 2/(Eu) disk coupled to a 5 cm long bundle of clear optical fibers, on average, /spl sim/250 photoelectrons are produced at a PMT photocathode for a /sup 204/Tl beta flood source (E/sub max/=763 keV). This corresponds to a sufficient number of photoelectrons for <1 mm resolution imaging capabilities for the proposed camera.
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