印度毛霉病爆发——是什么导致了这场危机?

R. Prasad, Sachana Prasad, R. Kumari, Komal khalkho, R. Choudhary
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摘要

这是一个回顾性研究分析人口统计、临床特征、放射性的发现和治疗的54例rhino-sino-orbital或脑毛霉菌病恰尔肯德邦三级医疗中心。所有可能或证实患有毛霉病的患者都被纳入研究。相当多(45%)的患者来自农村地区。约20%的患者无COVID感染史,提示轻度或无症状的COVID患者与毛霉菌病有关。在寻求医疗护理方面有大约11天的延迟,导致患者预后较差。糖尿病是与83%的患者相关的主要危险因素。80%的COVID - 19患者给予类固醇治疗。在37%的患者中发现广泛的疾病,这表明与covid前相比,毛霉病在暴发期间更具破坏性。
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Mucormycosis outbreak in India - What lead us to this crisis?
This is a retrospective study analysing the demographics, clinical characteristics, radiological findings and treatment of the 54 patients of rhino-sino-orbital or cerebral mucormycosis in a tertiary health care centre in Jharkhand. All patients with probable or proven mucormycosis were included in the study. A significant number (45%) of patients belonged to rural areas. About 20% of patients did not give history of COVID infection denoting association of mucormycosis in mild or asymptomatic COVID patients. There was a delay of approximately 11 days in seeking medical care leading to poorer outcome in patients. Diabetes was a major risk factor associated with 83% of the patients. Steroid was given as treatment in 80%of the patients who had COVID - 19. Extensive disease was seen in 37% of the patients suggesting that the mucormycosis was more devastating during the outbreak as compared to pre- covid times.
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