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Biofilms in the middle ear: Unveiling challenges and solutions 中耳生物膜:揭示挑战与解决方案
Pub Date : 2024-05-15 DOI: 10.18231/j.ijoas.2024.001
Manish Gupta
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引用次数: 0
Nasopharyngeal carcinoma in a young adolescent with unilatral palatal palsy and neck mass – A rare case report 一名患有单侧腭麻痹和颈部肿块的青少年鼻咽癌--罕见病例报告
Pub Date : 2024-05-15 DOI: 10.18231/j.ijoas.2024.006
Parmod Jangra, Bhavesh Kumar, Pratik Kumar, Bamin Nenkha
Less than 1% of all head and neck neoplasms are juvenile nasopharyngeal angiofibromas, a cancer almost exclusively found in adolescent males. Here we present a case report of 14 year old male presented with neck swelling, nasal discharge mixed with blood, right sided proptosis and right sided palatal palsy where we performed CECT scan of the patient which showed homogenous opacity over nasopharynx extending to soft palate and posteriorly to C1 vertebra and DNE was performed. Later patient was planned for DNE along with biopsy which came out to be undifferentiated non-keratinized squamous cell carcinoma grade III. Further patient received external beam intensity modulated radiation therapy with complete response to treatment.
在所有头颈部肿瘤中,青少年鼻咽血管纤维瘤占不到1%,这种癌症几乎只发生在青少年男性身上。我们在此报告了一例 14 岁男性患者的病例,患者颈部肿胀、鼻腔分泌物混有血液、右侧突眼和右侧腭麻痹,我们对患者进行了 CECT 扫描,结果显示患者鼻咽部有同质混浊物,并延伸至软腭和 C1 椎体后方,于是对患者进行了 DNE 扫描。随后,我们计划对患者进行 DNE 和活组织检查,结果显示为未分化非角化鳞状细胞癌 III 级。随后,患者接受了体外射束调强放射治疗,治疗后反应良好。
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引用次数: 0
Comparison of surgical outcome of endoscopic DCR using gouge or drill with or without stent 使用凿子或钻头(带或不带支架)进行内窥镜 DCR 的手术效果比较
Pub Date : 2024-05-15 DOI: 10.18231/j.ijoas.2024.002
Kamalpreet Singh, Amrindarjeet Kour, Poonam Raj, Arun Gupta
The aim of the study was to evaluate the longterm results of endoscopic endonasal dacryocystorhinostomy in the management of epiphora due to nasolacrimal duct obstruction.The prospective study included 30 patients of all age and either sex with features of dacrocystitis. Patients were randomly distributed for one of the following surgeries - Dacryocysto-rhinostomy using Stent and Powered instruments (STPI) / Dacryocysto-rhinostomy using Stents and Gouge (STGO) / Dacryocysto-rhinostomy using Powered instruments (NSPI) / Dacryocysto-rhinostomy using only Gouge (NSGO). Follow up till 365 days was done and data on outcome, recurrence and complications were collected.: Success rate of all the procedures were 100 % at Day 3 and Day 7. On Day 30, success rate of all the procedures except NSGO were 100 %. At day 90 and 180, success rates were NSGO (85.7%); NSPI (100%); STGO (100%); STPI (85.7%). At day 365, success rates were NSGO (57.1%); NSPI (100%); STGO (100%); STPI (71.4%). The difference was not statistically significant (p <0.05). The results indicate that the success rate of all the four modalities are comparable. : Endoscopic DCR is a safe day-care procedure done which can be done under local anaesthesia with excellent results. Its efficacy ranges from 85.7-100% on Day 90 and 180; and 57.1-100% on Day 365. Success rate of all four procedures are same. In view of high success rate and low complications with all four procedures (NSGO; NSPI; STGO; STPI), endoscopic DCR using gouge or drill with or without stent were recommended.
这项前瞻性研究纳入了30名具有泪囊炎特征的患者,年龄不限,性别不限。患者被随机分配接受以下手术之一--使用支架和动力器械的泪囊鼻腔造口术(STPI)/使用支架和挖孔器的泪囊鼻腔造口术(STGO)/使用动力器械的泪囊鼻腔造口术(NSPI)/仅使用挖孔器的泪囊鼻腔造口术(NSGO)。所有手术在第 3 天和第 7 天的成功率均为 100%。第 30 天,除 NSGO 外,所有手术的成功率均为 100%。第 90 天和第 180 天,成功率分别为 NSGO(85.7%);NSPI(100%);STGO(100%);STPI(85.7%)。在第 365 天,成功率分别为 NSGO(57.1%);NSPI(100%);STGO(100%);STPI(71.4%)。差异无统计学意义(P <0.05)。结果表明,所有四种方式的成功率相当。 内镜下 DCR 是一种安全的日间护理手术,可在局部麻醉下进行,效果极佳。第 90 天和第 180 天的有效率为 85.7%-100%,第 365 天为 57.1%-100%。四种手术的成功率相同。鉴于所有四种手术(NSGO、NSPI、STGO、STPI)的成功率高且并发症少,因此推荐使用带或不带支架的凿子或钻头进行内镜下 DCR。
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引用次数: 0
Cocktail regimen in treatment of sudden sensorineural hearing loss 治疗突发性感音神经性听力损失的鸡尾酒疗法
Pub Date : 2024-05-15 DOI: 10.18231/j.ijoas.2024.003
Anusha Venkatraman, Santosh Balasaheb Mane, Kamalika Purkayastha Roy, Poonam Khairnar
This study aims to evaluate the efficacy of a cocktail regimen for the treatment of sudden sensorineural hearing loss (SSNHL). A prospective observational study. Tertiary care hospital. Thirty-five patients diagnosed with SSNHL who met the inclusion criteria. The cocktail regimen included intratympanic steroid injections, oral steroids, valacyclovir, and pentoxifylline. The primary outcome was the change in Pure Tone Audiometry (PTA) from pre-treatment to 3 months post-treatment, analyzed by Modified Siegel’s criteria. Of the 35 patients, 26 (74.2%) showed hearing improvement (including complete and partial recovery) at the 3-month follow-up. The mean improvement in PTA was 22.56 dB (SD = 18.4). However, the calculated odds ratios (OR) for treatment efficacy and hearing recovery comparisons were 1.0, with wide confidence intervals, indicating no statistically significant differences between improved and not improved groups. The cocktail regimen showed potential benefits for hearing recovery in SSNHL patients, particularly in cases with less severe initial hearing loss. Nevertheless, the absence of a statistically significant difference in the comparative analyses underscores the need for larger, randomized controlled trials to substantiate these findings.
本研究旨在评估鸡尾酒疗法治疗突发性感音神经性听力损失(SSNHL)的疗效。前瞻性观察研究。三甲医院。35名符合纳入标准的突发性感音神经性听力损失患者。鸡尾酒疗法包括鼓室内类固醇注射、口服类固醇、伐昔洛韦和喷托维林。主要结果是纯音测听(PTA)从治疗前到治疗后 3 个月的变化,按照改良西格尔标准进行分析。在 35 名患者中,26 人(74.2%)在 3 个月的随访中听力有所改善(包括完全恢复和部分恢复)。PTA 的平均改善幅度为 22.56 分贝(标准差 = 18.4)。然而,计算得出的治疗效果和听力恢复比较的几率比(OR)均为 1.0,置信区间较宽,表明听力改善组和听力未改善组之间没有显著的统计学差异。鸡尾酒疗法显示出对 SSNHL 患者听力恢复的潜在益处,尤其是对初始听力损失不太严重的病例。尽管如此,比较分析中没有统计学意义上的显著差异突出表明,需要进行更大规模的随机对照试验来证实这些发现。
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引用次数: 0
A case report on use of ivermectin as nasal drop in a case of nasal myiasis 使用伊维菌素滴鼻剂治疗鼻霉菌病的病例报告
Pub Date : 2024-05-15 DOI: 10.18231/j.ijoas.2024.004
S. Vaidya, Vartika Paliwal
We describe a case of nasal myiasis due to in a 52-year-old Hindu priest with a previously known case of right sided hemiparesis with diabetes mellitus. Initial attempts to remove the fly larvae using manual extraction with a toothed forceps and normal saline irrigation were unsuccessful. On subsequent nasal irrigation after instillation of ivermectin tabs crushed in normal saline as nasal drops, the patient self-expulsed some larvae, and rest larvae were cleared on subsequent nasal suction and clearance. He also received a course of oral ivermectin. Here, we propose that the antiparasitic oral tablet ivermectin can be used in a nasal drop formulation for the aid of nasal myiasis.
我们描述了一例 52 岁印度教牧师的鼻肌炎病例,该牧师曾患有右侧肢体偏瘫和糖尿病。最初尝试使用带齿镊子和生理盐水进行人工拔除,但未能成功清除苍蝇幼虫。随后,患者在鼻腔中滴入用生理盐水碾碎的伊维菌素片剂后进行了鼻腔冲洗,自行排出了一些幼虫,其余幼虫在随后的鼻腔抽吸和清理中被清除。他还接受了一个疗程的伊维菌素口服治疗。在此,我们建议将伊维菌素抗寄生虫口服片剂制成滴鼻剂,用于辅助治疗鼻霉菌病。
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引用次数: 0
Massive mandibular ameloblastoma masquerading malignancy: A unique case 伪装成恶性肿瘤的巨大下颌骨釉母细胞瘤:一个独特的病例
Pub Date : 2024-05-15 DOI: 10.18231/j.ijoas.2024.005
Rakesh Kumar Singh, S. Jha, Mani Mala, Amod Kumar, Sanjeet Goit
Ameloblastomas are odontogenic tumours that arise from the maxilla and mandible. They are mostly benign but can seldom turn malignant. Their low incidence (<1-3%) and ambiguous presentation can often pose a diagnostic dilemma for the clinician. They are mostly diagnosed with the help of contrast-enhanced computed tomography scans and confirmed by characteristic findings on histopathological examination. We present a case of a 14-year-old boy presenting with a firm to hard external swelling on the right side of his face and extensive intraoral mass, which showed features of a bony malignancy but was subsequently diagnosed with ameloblastoma.
釉母细胞瘤是源于上颌骨和下颌骨的牙源性肿瘤。它们大多是良性的,但很少会转变为恶性。釉母细胞瘤发病率低(<1-3%),表现模糊,常常给临床医生带来诊断难题。它们大多通过造影剂增强计算机断层扫描来诊断,并通过组织病理学检查的特征性结果来确诊。我们介绍了一例 14 岁男孩的病例,他的右侧面部出现坚硬的外部肿物和广泛的口腔内肿块,显示出骨质恶性肿瘤的特征,但随后被诊断为釉母细胞瘤。
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引用次数: 0
Impacted ear drop dispenser cap: A rare cause of recurrent otitis externa 嵌塞式滴耳器帽:外耳炎复发的罕见原因
Pub Date : 2023-08-15 DOI: 10.18231/j.ijoas.2023.012
Parmod Jangra, J. Gulia, N. Saini
: To report a case of an elderly male with aural foreign body presenting as recurrent otitis externa and to highlight the fact that aural foreign bodies may be an underlying cause in such recurrent cases.: Case report: Aural foreign body with recurrent otitis externa.: Tertiary care center.: Surgical removal of foreign body. : The granulations and recurrent otitis externa resolved after removal of foreign body.: Suspicion of an aural foreign body should be maintained in a child or even adult presenting with recurrent otitis externa.
目的:报告一例老年男性外耳异物表现为复发性外耳炎,并强调在此类复发病例中,外耳异物可能是潜在原因。1例报告:耳异物伴复发性外耳炎。三级保健中心。异物的外科手术。:异物取出后,颗粒及复发性外耳炎消失。对于患有复发性外耳炎的儿童甚至成人,应保持对听觉异物的怀疑。
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引用次数: 0
Triple whammy in pandemic: COVID-19, mucormycosis and myiasis 大流行的三重打击:COVID-19、毛霉病和蝇病
Pub Date : 2023-08-15 DOI: 10.18231/j.ijoas.2023.014
Rachit Sood, A. Bhardwaj, M. Priya, Arpana Singh, Y. Mathuria, Suji PS, Rosy Saikia, M. Malhotra
Mucormycosis is a fatal opportunistic fungal infection most commonly seen in immunocompromised individuals. The mortality can vary depending on the extent of the disease, starting in the paranasal sinuses, reaching the orbit, and eventually spreading intracranially. The sudden surge of Mucormycosis along with COVID-19 infections has rightfully been described as an epidemic amidst a pandemic. While the exact etiological factor is still being investigated, uncontrolled diabetes seems to be the most common inciting factor. Mucormycosis being angioinvasive, often leads to thrombus formation in the vessels, which leads to the necrosis of the tissues and bones, most commonly the maxilla. This necrotic tissue forms an ideal culture for various organisms and is a potential source for maggots' infestation. The presence of nasal myiasis further worsens the clinical status of the patients, making them prone to life-threatening complications. Thus, nasal myiasis seems to be an independent prognosticating factor in such cases. Here, we have described two such cases, our approach to management and mortality despite the best possible management.Two cases are being presented of elderly patients with comorbidities of type 2 diabetes mellitus and coronary artery disease. Both patients had a recent onset of COVID-19 and presented with intraorbital and intracranial disease extension along with nasal myiasis. Both patients succumbed to the fulminant pathology despite aggressive management.Mucormycosis, COVID-19 and nasal myiasis combine together to form a fatal triad, which despite early identification and aggressive management, carries a poor prognosis.
毛霉病是一种致命的机会性真菌感染,最常见于免疫功能低下的个体。死亡率可根据疾病的程度而变化,从鼻窦开始,到达眼眶,最终向颅内扩散。毛霉病和COVID-19感染的突然激增被正确地描述为大流行中的流行病。虽然确切的病因仍在调查中,但不受控制的糖尿病似乎是最常见的诱因。毛霉菌病是血管侵入性的,经常导致血管血栓形成,从而导致组织和骨骼坏死,最常见的是上颌骨。这种坏死组织形成了各种生物的理想培养物,也是蛆虫侵扰的潜在来源。鼻蝇蛆病的存在进一步恶化了患者的临床状况,使他们容易发生危及生命的并发症。因此,鼻蝇蛆病似乎是一个独立的预测因素,在这种情况下。在这里,我们描述了两个这样的案例,我们的管理方法和死亡率,尽管最好的管理。2例老年患者合并2型糖尿病和冠状动脉疾病。两例患者均为新近发病的COVID-19,均表现为眼眶内和颅内疾病扩展并伴有鼻窦炎。尽管进行了积极的治疗,但两例患者都屈服于暴发性病理。毛霉病、COVID-19和鼻蝇病共同构成致命的三联体,尽管及早发现并积极治疗,但预后较差。
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引用次数: 0
Outcomes of endoscopic guided adenoidectomy versus conventional adenoidectomy 内镜引导下腺样体切除术与常规腺样体切除术的结果
Pub Date : 2023-08-15 DOI: 10.18231/j.ijoas.2023.010
Rinshin T, R. Bhandary
: Adenoidectomy is one of the most common surgical procedures performed on children. Conventional curettage adenoidectomy is a low-cost procedure that is still widely practised, particularly in developing nations. To compare conventional curettage adenoidectomy and endoscopic-assisted powered adenoidectomy using a microdebrider. Consecutive cases for Conventional Adenoidectomy (Group I) and Endoscopic Assisted Adenoidectomy (Group II) were taken from cases undergoing adenoidectomy, with each group consisting of 20 patients. The operating time and postoperative pain score were measured and compared between the two groups. Patients were evaluated at the first and sixth weeks to measure subjective improvement of symptoms , DNE was performed to evaluate remaining adenoid tissue and scarring of adjacent structures. The total operating time in groups I and II was 13 minutes (range: 10-15 minutes) and 21 minutes (range: 15-25 minutes), respectively. In 12 cases, remnent adenoid tissue ranged from 25 to 50%. Ten of them received conventional adenoidectomy. Group I experienced significantly higher postoperative pain than group II. Endoscopic adenoidectomy is a safe and effective alternative to conventional curettage. It favours consistent restoration of nasopharyngeal patency, improved haemostasis, and reduced postoperative pain.
腺样体切除术是儿童最常见的外科手术之一。传统的刮除腺样体切除术是一种低成本的手术,在发展中国家仍被广泛应用。比较传统刮刮式腺样体切除术和内镜辅助下使用微型清氧器的动力腺样体切除术。选取连续行常规腺样体切除术(I组)和内镜辅助腺样体切除术(II组)的病例,每组20例。比较两组手术时间和术后疼痛评分。在第1周和第6周对患者进行评估,以衡量主观症状的改善,DNE用于评估剩余的腺样体组织和邻近结构的瘢痕形成。I组和II组总手术时间分别为13分钟(范围:10 ~ 15分钟)和21分钟(范围:15 ~ 25分钟)。在12例中,残存腺样体组织在25 - 50%之间。其中10例行常规腺样体切除术。I组术后疼痛明显高于II组。内镜下腺样体切除术是一种安全有效的替代传统刮除。它有利于持续恢复鼻咽通畅,改善止血,减少术后疼痛。
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引用次数: 0
Vocal analysis of kindergarten and nursery school teachers 幼儿园教师声乐分析
Pub Date : 2023-08-15 DOI: 10.18231/j.ijoas.2023.013
Rohan Shetty, Vishwas K. Pai
What distinguishes humans from rest of the animal kingdom, is ability to convey ideas, emotions and complex deductive logic by the human faculty referred to as speech which in turn is fundamentally dependent on tones produced by voice box or the larynx .Communication ability is a must in the present day scenario and the inability to do so leads to a lot of unpleasentness in an individual. Abuse of the same leads to numerous problems ranging from fatigue or inability to speak for long to strain and sometimes severe dysphonia affecting the normal chores of day to day living and such an upset can lead to severe depression and inferiority complexes especially in people who need voice in their profession which includes teachers, call center employees, radio jockeys, trainers, motivational speakers. With all this in mind the following study was designed to exactly understand the problem and to come up with a solution if any to counter it.
人类与其他动物王国的区别在于,人类的语言能力能够传达思想、情感和复杂的演绎逻辑,而人类的语言能力则主要依赖于喉部发出的声音。在当今的环境中,沟通能力是必须的,而无法做到这一点会给个人带来很多不愉快。同样的滥用会导致许多问题,从疲劳或无法长时间说话到紧张,有时严重的语音障碍会影响日常生活的正常琐事,这种不安会导致严重的抑郁和自卑情结,特别是在那些需要声音的职业中,包括教师,呼叫中心员工,电台主持人,培训师,励志演说家。考虑到这一切,下面的研究旨在准确地理解这个问题,并提出一个解决方案,如果有的话。
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引用次数: 0
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IP Journal of Otorhinolaryngology and Allied Science
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