冬眠瘤是一种罕见部位的罕见肿瘤

Himachal Mishra, Manika Alexander
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摘要

冬眠瘤是一种罕见的良性肿瘤,起源于棕色脂肪。冬眠瘤被认为起源于含有残余棕色脂肪的区域,如肩胛间区、腋窝、颈部、胸部、腹腔和腹膜后。这种罕见的肿瘤很少发生在前额。作为一种良性肿瘤,未见与恶性转化或转移相关的报道。一名23岁男性,因过去6个月前额无痛性非进行性肿胀而主诉。检查肿胀2x2 cm,柔软,可移动,无压痛,无搏动,无皮肤改变。FNAC显示脂肪细胞呈片状和簇状,胞浆呈丰富泡沫状,报告为“冬眠瘤”。患者已被要求随访,在过去的一年里,肿瘤仍然没有进展,没有压力症状,因此没有接受手术。冬眠瘤是一种罕见的棕色脂肪组织良性肿瘤,仅占良性脂肪瘤肿瘤的1.6%,但其实际患病率尚不清楚。这种肿瘤很少发生在前额区域,虽然发生在前额的病例很少有报道。由于此肿瘤生长缓慢,无痛无进展;它通常表现为无症状的肿瘤。它必须包含在含脂肪细胞肿瘤的鉴别诊断中,以防止错误治疗。
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Hibernoma-A rare tumor on rare site
Hibernoma is a rare benign tumor that originates from brown fat. Hibernoma is thought to arise from areas containing residual brown fat like- the interscapular area, axilla, neck, chest, abdominal cavity, and retroperitoneum. The incidence of this rare tumor has very rarely been reported to occur over the forehead. Being a benign tumor, no association of malignant transformation or metastasis has been reported. A 23-year-old male presented with a complaint of a painless non-progressive swelling over the forehead for the past 6 months. On examination, the swelling was 2x2 cm, soft, mobile, non-tender, and non-pulsatile with no skin changes. FNAC did which shows sheets and clusters of adipocytes with abundant foamy cytoplasm and reported as “Hibernoma”. The patient has been asked to follow up and for the last 1 year, the tumor is still non-progressive with no pressure symptoms and hence has not undergone surgery. Hibernoma is a rare benign tumor of brown fat tissue which constitutes only 1.6% of benign lipomatous tumors but their actual prevalence is still unknown. This tumor very rarely may occur in the forehead area although incidence over the forehead has rarely been reported. Since this tumor is slow growing, painless non-progressive; it mostly presents as an asymptomatic tumor. It has to be included in the differential diagnosis of adipocyte-containing tumors to prevent false treatment.
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