酒精性心肌病:文献综述

Aina Zurohidah, Mustika Chasanatusy Syarifah
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引用次数: 0

摘要

背景:心肌病是一种心肌疾病,使心脏不能最佳收缩。酒精性心肌病是一种由于长期饮酒而扩张的心肌病。酒精性心肌病的患病率男性高于女性。酒精性心肌病发病最多的年龄组为45 ~ 74岁。死于酒精性心肌病的尸检结果显示肌肉扩张。毒理学检查可以显示饮酒的程度。酒精性心肌病的死亡原因是由于慢性酒精滥用引起的肌肉扩张(Dolinak, 2005)。伊斯兰教明确禁止一些使人失去理智的东西,比如酒精。酒精对消费者有许多不利之处,如失去理智和远离真主。目的:了解酒精性心肌病的定义、病理生理、临床表现及治疗方法。此外,从死亡和伊斯兰观点的角度认识和解释酒精性心肌病。方法:本研究设计为文献综述或图书馆综述,通过对已发表的研究进行识别、评价和综合,是一种系统、直接、可重复的研究方法。结果:酒精性心肌病是一种临床诊断,患者有一系列表现,包括过量饮酒史、可能的酒精滥用体征(如腮腺疾病、毛细血管扩张或蜘蛛血管瘤、精神状态改变、肝硬化)、心力衰竭和其他与扩张型心肌病一致的证据。经常饮酒的人会引起营养失调,尤其是维生素B1缺乏会引起心肌病。酒精还会导致心脏细胞线粒体的结构和功能异常。这些异常包括线粒体结构增大、代谢降低、几种酶缺乏、离子运输减少、钙流量增加、糖原积累和ATP产生减少。结论:心肌病是一种心肌功能障碍,其特征是心肌失去泵血能力,导致供血不佳而导致死亡。最常见的原因是长期饮酒,这会导致心肌扩张。与此同时,酒精是一种被穆斯林禁止食用的成分,因为它的影响更大。
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Alcoholic Cardiomyopathy: A Literature Review
Background: Cardiomyopathy is a heart muscle disorder so which the heart cannot contract optimally. Alcoholic cardiomyopathy is a type of cardiomyopathy that dilates due to long-term alcohol consumption. The prevalence of alcoholic cardiomyopathy is higher in men than women. The age group with the most alcoholic cardiomyopathy was 45 to 74 year. Death from alcoholic cardiomyopathy had an autopsy result marked muscle dilatation. A toxicological examination can show the level of alcohol consumed. The cause of death in alcoholic cardiomyopathy is muscle dilatation due to chronic ethanol abuse (Dolinak, 2005). Islam expressly forbids something that makes losing mind, like alcohol. Alcohol has many disadvantages for the consumer in the form of loss of mind and turning away from Allah. Objective: This report aims to learn more about the definition, pathophysiology, clinical manifestation, and treatment of Alcoholic Cardiomyopathy. Also, Knowing and explaining Alcoholic Cardiomyopathy in terms of death and Islamic views. Methods: The design of this research is a literature review or library review, which is a systematic, direct, and reproducible research method by identifying, evaluating, and synthesizing published research.  Result: Alcoholic cardiomyopathy is a clinical diagnosis made in a patient with a set of findings that include a history of excessive alcohol consumption, possible physical signs of alcohol abuse (e.g., parotid disease, telangiectasia or spider angiomata, altered mental status, cirrhosis), heart failure, and other evidence consistent with dilated cardiomyopathy. People who frequently consume alcohol can cause nutritional disorders, especially vitamin B1 deficiency can cause cardiomyopathy. Alcohol will also cause abnormalities in the structure and function of mitochondria in heart cells. These abnormalities include enlarged mitochondrial structure, decreased metabolism, lack of several enzymes decreased ion transport, increased calcium flow, glycogen accumulation, and decreased ATP production. Conclusion: Cardiomyopathy is a heart muscle function disorder characterized by the loss of the ability of the heart muscle to pump blood so that the blood supply is not optimal and results in death. The most common cause is chronic alcohol consumption, which causes dilatation of the heart muscle. At the same time, alcohol is an ingredient that is forbidden to be consumed by Muslims because of its more significant impact.
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