剖腹手术治疗何杰金氏病

F Bauters, J P Jouet, M T Caulier, A Wurtz, M Ribet, M Goudemand
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引用次数: 0

摘要

我们对70例霍奇金病患者进行了开腹和脾切除术。在43例探查前I期或II期患者中,16例(37.2%)剖腹探查时发现腹部定位被忽视。16例患者中有13例发生脾脏受累,单独受累(5例),伴淋巴结阳性(4例)或伴淋巴结阳性并伴肝脏受累(4例)。在勘探前的4个阶段中,未发现回归。在9例假定为横膈膜以上I期或II期且既往接受放疗的患者中,延迟开腹手术发现6例腹部复发。最后,在14例II期或IV期明显且既往联合化疗的患者中,因持续进化征象导致开腹时膈下残余定位8例。根据这些结果,我们建议在膈肌以上几乎所有假定的I期或II期立即开腹手术。这些患者中约有三分之一的患者的分期已进展到III期或IV期,根据我们的研究,必须采用联合化疗治疗,而其余病例则需要放疗。在明显的第三和第四期,延迟剖腹手术在化疗后的某些情况下可能是有用的。
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[Laparotomy in the therapy of Hodgkin's disease].

We have performed laparotomy and splenectomy for seventy patients with Hodgkin's disease. Among 43 stages I or II before exploration, primary laparotomy revealed ignored abdominal localizations in 16 cases (37,2%). Involvement of the spleen occurred in 13 of these 16 patients, lonely (5 cases), associated with positive nodes (4 cases) or associated with positive nodes and liver involvement (4 cases). Among 4 stages III before exploration, no regression was found. Among 9 patients with presumed stages I or II above the diaphragm and previously treated by radiotherapy, delayed laparotomy revealed abdominal relapse in 6 cases. At last, among 14 patients with obvious stages II or IV and previously treated by combination chemotherapy, laparotomy, caused by persistent evolutive signs, showed residual localizations under the diaphragm in 8 cases. According to these results, we preconise immediate laparotomy in almost all presumed stages I or II above the diaphragm. About third of these subjects have their staging advanced to stage III or IV and, according to us must be treated by combination chemotherapy while the remaining cases justify of radiotherapy. In obvious stages III and IV delayed laparotomy may be useful in some circumstances, after chemotherapy.

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