犬抗狂犬病疫苗的研究

S. Kondo
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引用次数: 1

摘要

1. 在实验室用动物制备和试验的各种疫苗中,一种是用感染了固定病毒的动物的脑和脐带的乳剂在37°C下孵育制备的。3天或室温保存10天制备的乳剂最适用于犬的疫苗接种。乳剂在37℃下孵育制备疫苗。比在室温下处理要好,因为前者可以使病毒的衰减更均匀。作为疫苗的来源,狗的脑和脊髓比兔的好,因为前者的产量是后者的6倍。在狗身上,疫苗应一次皮下接种,剂量为5cc .5。疫苗产生的免疫力持续约一年。
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ON THE ANTI-RABIC VACCINATION IN THE DOG
1. Of various vaccines which were prepared and tested on animals in the laboratory, the one prepared by incubating the emulsion of the brain and cord from animals infected with fixed virus at 37°C. for 3 days or that prepared by keeping the emulsion at room temperature for 10 days is most applicable for the vaccination in the dog.2. The vaccine prepared by incubating the emulsion at 37°C. is better than that prepared by keeping it at room temeprature, because more uniform attenuation of the virus could be expected in the former treatment.3. As the source of the vaccine the brain and cord of the dog is better than those of rabbit, because the yield in the former is six times more than that in the latter.4. In the dog the vaccine is to be once inoculated subcutaneously in dose of 5c.c.5. The immunity produced by the vaccination lasts for about one year.
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