用于同步神经电和神经化学检测的双模式神经信号记录系统

Shengwei Xu, Nansen Lin, Dalei Wang, Wenjing Yu, W. Shi, Tingjun Jiang, Xinxia Cai
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引用次数: 1

摘要

本文介绍了一种64通道双模神经信号记录系统(DMNSRS),用于检测神经电信号和神经化学信号。DMNSRS由电流分辨率为1 pA的神经化学记录模块和电压分辨率为0.3 μV的神经电记录模块组成。两个模块可以同步工作,互不干扰。在全脑缺血实验中,采用多电极阵列(MEA)作为神经生物电极,单壁碳纳米管(SWNT)修饰的玻碳电极作为神经化学工作电极,用DMNSRS同步记录SD大鼠皮层的神经电和神经化学信号。
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A Dual Mode Neural Signal Recording System for synchronous neuroeletrical and neurochemical detection
This paper presents a 64-channel Dual Mode Neural Signal Recording System (DMNSRS) for detection of neuroeletrical and neurochemical signals. The DMNSRS comprises neurochemical recording module with current resolution of 1 pA and neuroelectricity recording module with voltage resolution of 0.3 μV. The two modules can work synchronously without mutual interference. In a global cerebral ischemia experiment, using Multi-Electrode Arrays (MEA) as neurobiological electrode and a single-walled carbon nanotube (SWNT)-modified glassy carbon electrode as neurochemical working electrode, the neuroelectrical and neurochemical signals are synchronously recorded by the DMNSRS in the Sprague-Dawley (SD) rat cortex.
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