静脉注射吸毒者中的丙型肝炎感染。“隐形人群中无声的疾病”

Khalid Saaran, Hamad Al-Ghaferi, Abuelgasim Elrasheed, Asma Awadhi, Ahmed. Y. Ali
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引用次数: 0

摘要

目的:肝炎被定义为肝脏的一种炎症。我们的目标是强调丙型肝炎(病毒性肝炎的一种亚型)对患有酒精使用障碍(AUD)和物质使用障碍(SUDs),特别是静脉注射吸毒者(IDUs),也被称为隐形人群的患者亚群的破坏性影响。我们也旨在描述临床图片,病毒基因型和可用的治疗。方法:进行文献综述,特别关注有关上述目标的出版材料。结论:丙型肝炎被认为是一个全球性的健康问题。被描述为一种“沉默的疾病”,其并发症包括肝硬化、终末期肝病和肝细胞癌、合并感染艾滋病毒和不同丙型肝炎病毒株的超感染。在了解丙型肝炎病毒病毒学方面的最新进展导致了针对复制过程的新药的开发,并证明在清除感染方面非常成功。值得注意的是,目前还没有针对丙型肝炎病毒感染的疫苗。
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Hepatitis C Infection among Intravenous Drug Users. “A Silent Disease in an Invisible Population”
Objective: Hepatitis is defined as an inflammation of the liver. Our objective is to highlight the devastating effects Hepatitis C, a subtype of viral hepatitis, has on a subpopulation of patients struggling with Alcohol use disorder (AUD) and SUDs (Substance Use Disorders) and specially IDUs, (Intravenous Drug Users) also known as the invisible population. We also aim to describe the clinical picture, viral genotypes and available treatments. Methods: A literature review was conducted, specifically looking at published materials about the objectives above. Conclusion: Hepatitis C is considered a global health problem. Described as a “silent disease” its complications include liver cirrhosis, end-stage liver disease and hepatocellular carcinoma, co-infection with HIV and super infections with different strains of HCV. Recent advances in understanding HCV virology have led to the development of new drugs targeting replication process and proving to be very successful in clearing the infection it is important to note that there is no vaccine yet for HCV infection.
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