运动障碍和糖尿病,一项来自南印度的研究

Shankar S Prabhu, N. Ramya
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引用次数: 2

摘要

目的:运动障碍,如舞蹈病,舞蹈病-偏瘫,舞蹈病已被证明早期与糖尿病。在我们的研究中,我们分析了与糖尿病相关的运动障碍的临床和影像学特征。方法:对入院的运动障碍患者进行糖尿病筛查。分析有糖尿病病史或新发糖尿病患者的临床表现和影像学特征,以及糖尿病治疗后运动障碍的恢复情况。结果:共有11例出现不自主运动的患者被发现患有糖尿病。其中,5例患者表现为半舞蹈症,3例表现为舞蹈症,2例表现为舞蹈症,1例表现为全身性舞蹈症。患者年龄在45-73岁之间。其中3例为糖尿病的首发症状,既往无糖尿病史。HbA1C评估的血糖状态非常差,所有11例患者的血糖值均超过10%。9例患者的CT表现为壳核区高密度。在所有患者中,不自主运动在糖尿病治疗后完全消失或减少。结论:运动障碍与糖尿病相关。早期识别这些运动障碍的临床和放射学特征是必要的,因为及时控制血糖状态将导致这些不自主运动的快速恢复,并有良好的预后。
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Movement Disorders And Diabetes, A Study From South India
Purpose: Movement disorders like chorea, hemichorea-hemiballismus, choreoathetosis has been documented earlier with diabetes mellitus. We in our study have analyzed clinical and radiological characteristics of movement disorders occurring in association with diabetes. Methods: Patients admitted with movement disorders were screened for the presence of Diabetes. Patients with history of diabetes or new onset diabetes were analyzed for their clinical presentation and radiological characteristics, and the recovery of movement disorders with treatment of diabetes. Results: A total of eleven patients who presented with involuntary movements were found to have diabetes. Of these, five patients presented with hemiballismushemichorea, three with hemichorea, and two patients with choreoathetosis and one with generalized chorea-ballismus. The age of the patients ranged between 45–73 years. In three patients, it was the presenting symptom of diabetes without any previous history of diabetes. The glycemic status as assessed by HbA1C was very poor, with values more than 10 % in all the 11 patients. In nine patients, the Brain CT showed hyperdensity in the region of putamen. In all the patients, the involuntary movements resolved completely or decreased with treatment of diabetes. Conclusion: Movement disorders are associated with diabetes. The early recognisation of the clinical and radiological features of these movement disorders is necessary, as prompt control of the glycemic status will result in rapid recovery of these involuntary movements and will have good prognosis.
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