M. Mardiyanti, W. Widada, Ratna Pelawati, E. Wulandari, Samsiah Samsiah
{"title":"Hijamah(拔罐疗法)对高胆固醇血症患者血脂及载脂蛋白的影响","authors":"M. Mardiyanti, W. Widada, Ratna Pelawati, E. Wulandari, Samsiah Samsiah","doi":"10.20884/1.jks.2022.17.2.5692","DOIUrl":null,"url":null,"abstract":"Hijamah or cupping therapy has a therapeutic effect on cholesterol. However, there is still a lack of studies that investigate the potential effect of cupping in managing apolipoprotein B as a proatherogenic agent and apolipoprotein A-1 as an anti-proatherogenic agent. This study aims to explore the effect of cupping therapy on lipid profiles and apolipoproteins in hypercholesterolemic patients. A pre-post experimental design without controls were used. Consecutive sampling was applied to 40 dyslipidemia respondents. The lipid profiles and plasma apolipoproteins A-I (ApoA-I) and apolipoproteins B (ApoB) were measured after the respondents fasted for 12 hours before cupping therapy and 24 hours after cupping therapy. The Wilcoxon sign-rank test was used for the data analysis. The following results were found: average lipid profile (mg/dL) and apolipoprotein (µg/mL) pre vs post cupping: Total Cholesterol (Pre-test vs Post-test) 328 vs 283 (P-value 0.003); TG 238 vs 204 (P- value 0.007); HDL 78.5 vs 85 (P- value 0.000); LDL 195 vs 158 (P- value 0.001); ApoA-1 0.07 vs 0.67 (P-value 0.000); ApoB 2.04 vs 1.82 (P-value 1.000); ApoB/ApoA-1 ratio 30.22 vs 2.93 (P- value 0.000); cholesterol/HDL ratio 4.06 vs 3.08 (P- value 0.332); TG/HDL ratio 3.01 vs 2.83 (P- value 0.104); LDL/ApoB ratio 90.75 vs 83.82 (P- value 0.0837). In conclusion, cupping therapy reduces total cholesterol, TG, LDL, and apoB/ApoA-1 ratio and increases HDL significantly in dyslipidemic patients. Nurses are suggested to include cupping therapy (hijamah) in their intervention for reducing hypercholesterolemia in dyslipidemic patients.","PeriodicalId":337731,"journal":{"name":"Jurnal Keperawatan Soedirman","volume":"35 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Therapeutic Effect of Hijamah (Cupping Therapy) on Lipid Profiles and Apolipoprotein in Hypercholesterolemic Patients\",\"authors\":\"M. Mardiyanti, W. Widada, Ratna Pelawati, E. Wulandari, Samsiah Samsiah\",\"doi\":\"10.20884/1.jks.2022.17.2.5692\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hijamah or cupping therapy has a therapeutic effect on cholesterol. However, there is still a lack of studies that investigate the potential effect of cupping in managing apolipoprotein B as a proatherogenic agent and apolipoprotein A-1 as an anti-proatherogenic agent. This study aims to explore the effect of cupping therapy on lipid profiles and apolipoproteins in hypercholesterolemic patients. A pre-post experimental design without controls were used. Consecutive sampling was applied to 40 dyslipidemia respondents. The lipid profiles and plasma apolipoproteins A-I (ApoA-I) and apolipoproteins B (ApoB) were measured after the respondents fasted for 12 hours before cupping therapy and 24 hours after cupping therapy. The Wilcoxon sign-rank test was used for the data analysis. The following results were found: average lipid profile (mg/dL) and apolipoprotein (µg/mL) pre vs post cupping: Total Cholesterol (Pre-test vs Post-test) 328 vs 283 (P-value 0.003); TG 238 vs 204 (P- value 0.007); HDL 78.5 vs 85 (P- value 0.000); LDL 195 vs 158 (P- value 0.001); ApoA-1 0.07 vs 0.67 (P-value 0.000); ApoB 2.04 vs 1.82 (P-value 1.000); ApoB/ApoA-1 ratio 30.22 vs 2.93 (P- value 0.000); cholesterol/HDL ratio 4.06 vs 3.08 (P- value 0.332); TG/HDL ratio 3.01 vs 2.83 (P- value 0.104); LDL/ApoB ratio 90.75 vs 83.82 (P- value 0.0837). In conclusion, cupping therapy reduces total cholesterol, TG, LDL, and apoB/ApoA-1 ratio and increases HDL significantly in dyslipidemic patients. 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引用次数: 0
摘要
Hijamah或拔火罐疗法对胆固醇有治疗作用。然而,关于拔罐对载脂蛋白B作为促动脉粥样硬化剂和载脂蛋白a -1作为抗动脉粥样硬化剂的潜在影响的研究仍然缺乏。本研究旨在探讨拔火罐治疗对高胆固醇血症患者血脂及载脂蛋白的影响。采用无对照的实验前后设计。对40名血脂异常患者进行连续抽样。受试者在拔罐前禁食12小时和拔罐后禁食24小时,分别测定血脂和血浆载脂蛋白A-I (ApoA-I)和载脂蛋白B (ApoB)。数据分析采用Wilcoxon符号秩检验。结果如下:拔罐前后的平均脂质谱(mg/dL)和载脂蛋白(µg/mL):总胆固醇(测前vs测后)328 vs 283 (p值0.003);TG 238 vs 204 (P值0.007);HDL 78.5 vs 85 (P值0.000);LDL 195 vs 158 (P值0.001);ApoA-1 0.07 vs 0.67 (p值0.000);ApoB 2.04 vs 1.82 (p值1.000);ApoB/ApoA-1比值30.22 vs 2.93 (P值0.000);胆固醇/高密度脂蛋白比值4.06 vs 3.08 (P值0.332);TG/HDL比值3.01 vs 2.83 (P值0.104);LDL/ApoB比值90.75 vs 83.82 (P值0.0837)。综上所述,拔火罐治疗可显著降低血脂异常患者的总胆固醇、TG、LDL和载脂蛋白/ApoA-1比值,并显著升高HDL。建议护士将拔罐疗法(hijamah)纳入其干预措施,以降低血脂异常患者的高胆固醇血症。
Therapeutic Effect of Hijamah (Cupping Therapy) on Lipid Profiles and Apolipoprotein in Hypercholesterolemic Patients
Hijamah or cupping therapy has a therapeutic effect on cholesterol. However, there is still a lack of studies that investigate the potential effect of cupping in managing apolipoprotein B as a proatherogenic agent and apolipoprotein A-1 as an anti-proatherogenic agent. This study aims to explore the effect of cupping therapy on lipid profiles and apolipoproteins in hypercholesterolemic patients. A pre-post experimental design without controls were used. Consecutive sampling was applied to 40 dyslipidemia respondents. The lipid profiles and plasma apolipoproteins A-I (ApoA-I) and apolipoproteins B (ApoB) were measured after the respondents fasted for 12 hours before cupping therapy and 24 hours after cupping therapy. The Wilcoxon sign-rank test was used for the data analysis. The following results were found: average lipid profile (mg/dL) and apolipoprotein (µg/mL) pre vs post cupping: Total Cholesterol (Pre-test vs Post-test) 328 vs 283 (P-value 0.003); TG 238 vs 204 (P- value 0.007); HDL 78.5 vs 85 (P- value 0.000); LDL 195 vs 158 (P- value 0.001); ApoA-1 0.07 vs 0.67 (P-value 0.000); ApoB 2.04 vs 1.82 (P-value 1.000); ApoB/ApoA-1 ratio 30.22 vs 2.93 (P- value 0.000); cholesterol/HDL ratio 4.06 vs 3.08 (P- value 0.332); TG/HDL ratio 3.01 vs 2.83 (P- value 0.104); LDL/ApoB ratio 90.75 vs 83.82 (P- value 0.0837). In conclusion, cupping therapy reduces total cholesterol, TG, LDL, and apoB/ApoA-1 ratio and increases HDL significantly in dyslipidemic patients. Nurses are suggested to include cupping therapy (hijamah) in their intervention for reducing hypercholesterolemia in dyslipidemic patients.