{"title":"碘酪氨酸-去卤酶缺乏症患者甲状腺素向三碘甲状腺原氨酸的正常转化。","authors":"F Ismail-Beigi, M Rahimifar","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>BMR, t1/2 of serum T4, and the conversion of T4 to T3 were normal in a patient with iodotyrosine-dehalogenase deficiency who had undergone total surgical thyroidectomy and had been maintained on 200 mug of oral T4 daily. It is concluded that the enzyme system for monodeiodination and conversion of T4 to T3 is different than iodotyrosine-dehalogenase.</p>","PeriodicalId":76301,"journal":{"name":"Pahlavi medical journal","volume":"7 4","pages":"484-90"},"PeriodicalIF":0.0000,"publicationDate":"1976-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Normal conversion of thyroxine to triiodothyronine in a subject with iodotyrosine-dehalogenase deficiency.\",\"authors\":\"F Ismail-Beigi, M Rahimifar\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>BMR, t1/2 of serum T4, and the conversion of T4 to T3 were normal in a patient with iodotyrosine-dehalogenase deficiency who had undergone total surgical thyroidectomy and had been maintained on 200 mug of oral T4 daily. It is concluded that the enzyme system for monodeiodination and conversion of T4 to T3 is different than iodotyrosine-dehalogenase.</p>\",\"PeriodicalId\":76301,\"journal\":{\"name\":\"Pahlavi medical journal\",\"volume\":\"7 4\",\"pages\":\"484-90\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1976-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pahlavi medical journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pahlavi medical journal","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Normal conversion of thyroxine to triiodothyronine in a subject with iodotyrosine-dehalogenase deficiency.
BMR, t1/2 of serum T4, and the conversion of T4 to T3 were normal in a patient with iodotyrosine-dehalogenase deficiency who had undergone total surgical thyroidectomy and had been maintained on 200 mug of oral T4 daily. It is concluded that the enzyme system for monodeiodination and conversion of T4 to T3 is different than iodotyrosine-dehalogenase.