正常压力脑积水

Maria Eduarda Turczyn de Lucca, L. Antunes, C. A. Rodriguez, O. Fustes
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引用次数: 0

摘要

常压脑积水- NPH是痴呆的潜在可逆原因之一。在这项工作中,我们为初级卫生保健- PHC医生提供了NPH管理的临床工具。我们回顾了PubMed和Cochrane数据库,并选择了40篇文章,其中包括随机临床试验、元分析和系统综述。经典三联症的症状是非特异性的,在患有其他疾病的老年人中也有发现。步态失用是最早的症状,其次是认知障碍和尿失禁。约60%的晚期病例会同时出现这三种症状。步态失用症表现为步幅短,没有感觉、前庭小脑或肌肉力量的变化,这使其与其他病理性行军相区别。认知障碍是皮层下的——精神运动缓慢、注意力不集中、工作记忆和执行功能的丧失以及情景记忆的保留——不同于皮层痴呆,如阿尔茨海默病。尿失禁必须与女性前列腺增生和压力性尿失禁区分开来。初级保健医生在面对这三种症状时,应要求进行CT扫描或脑MRI,如果出现一种或两种症状,应排除其他诊断。NPH患者向初级保健中心的医生寻求帮助,初级保健中心的医生必须知道如何识别和区分他们的症状。在怀疑的情况下,神经影像学的研究是强制性的,推荐转诊到神经外科或神经病学。
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Normal pressure hydrocephalus
Normal pressure hydrocephalus – NPH is one of the potentially reversible causes of dementia. In this work, we provide the clinical tools for the management of NPH to the Primary Health Care – PHC physicians. The PubMed and Cochrane databases were reviewed, and 40 articles were chosen, which include randomized clinical trials, metanalysis and systematic reviews. The symptoms of the classic triad are nonspecific and found in the elderly with other diseases. Gait apraxia is the earliest symptom, followed by cognitive impairment and urinary incontinence. The concomitance of the three symptoms occurs in about 60% of the cases in the advanced stages. Apraxia of gait is presented with short steps, without sensorial, vestibulocerebellar or muscle strength changes, which allows it to be distinguished from other pathological marches. Cognitive impairment is subcortical – psychomotor slowliness, inattention, loss of working memory and executive function and preservation of episodic memory – unlike cortical dementias, such as Alzheimer's disease. Urinary incontinence must be distinguished from overflow by prostatism and stress incontinence in women. The PHC physician, when faced with the triad, should request a CT scan or brain MRI and, in the presence of one or two symptoms, rule out other diagnoses. Patients with NPH seek help from the physician in the PHC who must know how to identify and differentiate their symptoms. In the case of suspicion, the study of neuroimaging is mandatory and referral to neurosurgery or neurology is recommended.
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