COVID-19大流行背景下的多发性硬化症

Sergey M. Karpov, I. Vyshlova, Anna I. Klimenko, E. Tkachenko, R. N. Gadaborshev, Akhshar I. Dzutsev
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引用次数: 0

摘要

多发性硬化症是一种严重的、可能致残的中枢神经系统疾病,通常会同时影响大脑和脊髓的几个区域。在俄罗斯已经发现了大量患有这种疾病的患者。多发性硬化症的病因仍在研究中。每年都会有关于不同因素的影响及其相互作用的新数据出现。现代科学正在积极研究多发性硬化症的进展机制、线粒体在炎症和神经退行性变中的作用以及COVID-19对多发性硬化症发生进展可能性的影响。在这篇综述中,我们将考虑SARS-CoV-2病毒对多发性硬化症病程的影响。
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Multiple sclerosis in the context of the COVID-19 pandemic
Multiple sclerosis is a serious, potentially disabling disease of the central nervous system that often affecting several areas of the brain and spinal cord at the same time. A large number of patients with this disease have been identified in Russia. The aetiology of multiple sclerosis is still under investigation. Every year, new data emerge on the influence of different factors and their interaction. Modern science is actively studying the mechanisms of multiple sclerosis progression, the role of mitochondria in inflammation and neurodegeneration, as well as the impact of COVID-19 on the possibility of development and progression of multiple sclerosis. In this review, we will consider the impact of the SARS-CoV-2 virus on the course of multiple sclerosis.
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