异常脑出血作为转移性肿瘤的术后并发症

S. Karamouzian
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摘要

本文描述脑转移诊断活检后的一个不寻常的并发症。我们收治了一位39岁的男性患者,他有最近发作的癫痫病史。MRI显示多发病变。对转移诊断的检查为阴性。他接受了病灶切除术。组织学检查发现转移性腺癌。手术后胼胝体出血恶化了他的神经系统状况。脑转移是系统性癌症患者发病率和死亡率的重要来源。在成人中,发病率最高的是在生命的第五至第七十年[1]。在该患者组中,最常见的脑转移源依次为肺癌、乳腺癌和皮肤癌[2]。在临床诊断为转移的患者中,多达10%至15%的患者实际上可能存在脓肿或原发肿瘤等非转移性病变[3]。因此,对于原发部位未知的患者,取样可以为确认转移的诊断提供组织。另一方面,术后出血被认为是手术的并发症。
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Unusual Intracerebral Hemorrhage as a Postoperative Complication of A Metastatic Tumor
Described here is an unusual complication after diagnostic biopsy for brain metastasis. We admitted a 39-year-old male patient with history of recent onset seizure. MRI revealed multiple lesion . Workup to diagnosis of metastasis was negative. He underwent a lesionectomy. Histological examination identified metastatic adenocarcinoma. After the surgery hemorrhage in corpus callosum deteriorated his neurological status. Brain metastases represent a significant source of morbidity and mortality in patients with systemic cancer. Among adults, the highest incidence is observed in the fifth to seventh decades of life[1]. The most common sources of brain metastases in this patient group are cancers of the lung, breast, and skin, in descending order[2]. As many as 10% to 15% of patients with a clinical diagnosis of metastasis may, in fact, have nonmetastatic lesions such as abscesses or primary tumors[3]. So in patients without known primary site of tumor, sampling can provide tissue for confirming the diagnosis of metastasis. In other hands post operative hemorrhage has been known as a complication of surgery.
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