{"title":"用于大规模神经记录的下一代头戴式显微镜","authors":"J. Scherrer, G. F. Lynch, Jie J. Zhang, M. Fee","doi":"10.1364/brain.2023.bm3b.2","DOIUrl":null,"url":null,"abstract":"We present a fluorescence microscope design that enables imaging of thousands of cortical neurons in freely-moving mice. The design eliminates traditional illumination optics, allowing for head-mounted microscopes with both a lower weight (1.4 gram) and a larger field-of-view (~4 mm diameter) than previously possible.","PeriodicalId":111173,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Next-generation head-mounted microscopes for large-scale neural recordings\",\"authors\":\"J. Scherrer, G. F. Lynch, Jie J. Zhang, M. Fee\",\"doi\":\"10.1364/brain.2023.bm3b.2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We present a fluorescence microscope design that enables imaging of thousands of cortical neurons in freely-moving mice. The design eliminates traditional illumination optics, allowing for head-mounted microscopes with both a lower weight (1.4 gram) and a larger field-of-view (~4 mm diameter) than previously possible.\",\"PeriodicalId\":111173,\"journal\":{\"name\":\"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)\",\"volume\":\"10 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1364/brain.2023.bm3b.2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/brain.2023.bm3b.2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Next-generation head-mounted microscopes for large-scale neural recordings
We present a fluorescence microscope design that enables imaging of thousands of cortical neurons in freely-moving mice. The design eliminates traditional illumination optics, allowing for head-mounted microscopes with both a lower weight (1.4 gram) and a larger field-of-view (~4 mm diameter) than previously possible.