尼日利亚Emekuku村农民肠道寄生虫负荷的实验室和超声评估

E. Odumeru, C. Njoku, C. Ewurum, K. Agwunobi
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摘要

背景:肠道寄生虫(IP)是一种生活在宿主体内并为伤害或互惠而斗争的生物,是一个全球关注的问题,感染了30多亿人,并在全世界约4.5亿人中造成发病率,其中发展中国家受影响最严重,大多数是学童、农村居民和农民。寄生负荷(PL)在我们的地方尚未评估,或确定,并根据农民的传记数据进行比较。目的:采用实验室检查和超声检查相结合的方法对埃马库库地区农民的肾上腺素含量进行测定。方法:采用有目的的非概率抽样方法,采用横断面研究设计,选取年龄在20 ~ 90岁的男女共126例。采集粪便标本,采用湿法制和浓缩法进行实验室调查和比较。超声检查用于确认和表征IP。数据分析采用简单描述性统计和卡方分析。结果:湿法阳性10例(7.94%),浓缩法阳性44例(34.92%)(P < 0.05);其中,类蚓蛔虫的发病率最高,以80 ~ 89岁年龄组发生率最高,占62.5%,女性发生率最高,占15.87%,差异有统计学意义(P =0.039967)。5个声像图指标中,有4个(80.0%)能确认IP。结论:超声检查补充了实验室粪便分析的作用,对IP的存在、特征、位置和并发症,如蚓状蛔虫。
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Laboratory and Sonographic Assessment of Intestinal Parasitic Load of Peasant Farmers in Emekuku Village in Nigeria
Background: Intestinal parasites (IP) are organisms that live and strife within the host for harm or mutual benefit, is a global concern infecting over 3 billion people and causing morbidity in about 450 million people worldwide of which the developing countries are most affected, the majority being school children, rural dwellers, and peasant farmers. Parasitic load (PL) in our locality has not been assessed, or determined, and comparisons made based on biographic data of the peasant farmers. Objective: The study was aimed at determining the PL of peasant farmers in Emekuku by Laboratory and Sonographic examinations. Methods: A cross-sectional study design with a purposive non-probability sampling technique was used to select 126 subjects within the age group of 20 years to 90 years of both sexes. Stool specimens were collected, Wet preparation and Concentration Methods were used for laboratory investigation and comparisons were made. Sonography was used for the confirmation and characterization of IP. Data were analyzed with simple descriptive statistics and chi-square. Results: Wet prep technique recorded 10 (7.94%) positive cases while the Concentration method recorded 44 (34.92%) positive cases (P < 0.05). Ascaris lumbricoides amongst other IPs had the highest manifestation in the study, most prevalent in the age group 80 to 89 years,10 (62.5%) and more occurring in the female 10 (15.87%) and significant (P =0.039967). Sonographic indices for confirmation of IP were 4 (80.0%) out of 5. Conclusion: Sonography complements the role of Laboratory stool analysis for the presence, characterization, location, and complications of IP such as Ascaris lumbricoides.
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