Magnetic Microfluidic Biosensor for the Detection and Quantification of Biomolecules

In this paper we present a novel, multiplex, portable microfluidic biosensor for real-time detection and quantification of biomolecules, such as proteins, antibodies, DNA strands and anti-cancer drugs conjugated with Fe3O4 nanoparticles. We show that quantification hands-on time is reduced, and sample throughput can be increased using automation and efficient data evaluation with the appropriate LabVIEW software. Experiments were carried out using Fe3O4 nanoparticles coated with Poly(lacticacid), PEG and Curcumin as a proof of concept.