犬消化道感染病理血液参数及共程序分析

S. Prosyanуi, Y. Horiuk
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摘要

介绍。人体对任何疾病的反应不仅要通过临床症状来评估,还要通过身体生物底物的研究结果来评估,这通常可以揭示所有系统和器官中发生的病理变化的程度和性质,这在选择最有效的治疗方案时很重要,也可以确定亚临床疾病和使用某些药物的禁忌症。目的。研究犬消化道感染病理的主要血液参数及其协同程序。方法。实验研究于2019-2021年进行。已经形成了两组动物进行研究:对照(健康动物)和实验(患有传染性肠炎的狗)。血液生化和泌尿学研究已使用普遍接受的方法进行。结果。在对消化道感染性病理犬临床主要血液参数的研究过程中,发现中度红细胞减少症、持续性白细胞减少症、少色症、低蛋白血症、血色指数、红细胞压积值下降、ESR升高。白细胞图参数提示中度中性粒细胞增多,淋巴细胞减少症明显表达,这可能导致免疫抑制的发生,从而导致更严重的病程。在犬传染性肠胃炎的复杂诊断中,对患病动物粪便的研究是相关的,这使得评估消化系统在这些病理中的功能状态成为可能。与同样饮食的健康动物相比,患有急性感染性肠病的狗的共同计划的特点是蛋白质、胆红素原、胆红素、未消化的淀粉、肥皂和中性脂肪的含量增加。结论。因此,在选择治疗药物时,应客观考虑犬消化道感染病理的血液参数变化和共程序。
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ANALYSIS OF BLOOD PARAMETERS AND COPROGRAM IN INFECTIOUS PATHOLOGIES OF THE ALIMENTARY TRACT IN DOGS
Introduction. The body’s reaction to any disease is assessed not only by clinical signs, but also by the results of studies of the body’s biological substrates, which often allow revealing the degree and nature of pathological changes that occur in all systems and organs, which is important when choosing the most effective treatment regimen, as well as to identify subclinical disorders and contraindications to the use of certain drugs. Purpose. The purpose of work – to investigate the main blood parameters and coprogram in infectious pathologies of the alimentary tract in dogs. Methods. Experimental research was conducted during 2019–2021. Two groups of animals have been formed for research: control (healthy animals) and experimental (dogs with infectious enteritis). Haemato-biochemical and coprological studies have been performed using generally accepted methods. Results. In the process of studying the main blood parameters of dogs clinically suffering from infectious pathologies of the alimentary tract, moderate erythrocytopenia, persistent leukocytopenia, oligochromemia, hypoproteinemia, a decrease in blood colour index, haematocrit value, and an increase in ESR have been found. Leukogram parameters indicate the development of moderate neutrophilia, clearly expressed lymphocytopenia, which probably leads to the occurrence of immunosuppression and, accordingly, a more severe course of the disease. In the complex diagnosis of infectious gastroenteritis in dogs, studies of the excrement of sick animals are relevant, which make it possible to assess the functional state of the digestive system in these pathologies. The coprogram of dogs with an acute course of infectious enteropathies, compared to healthy animals on the same diet, has been characterized by an increased content of protein, stercobilinogen, bilirubin, undigested starch, soaps and neutral fat. Conclusion. Thus, changes in blood parameters and coprogram in infectious pathologies of the alimentary tract of dogs should be objectively taken into account when choosing therapeutic agents for their effective treatment.
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