网窝病:临床意义及治疗

M. Ekim, H. Ekim
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摘要

网状斑痣(LR)是一种色素沉着的皮肤变色,其特征是紫色,网状的紫绀型,多见于四肢和躯干。LR以完整的圆形网络的形式存在。如果圆形网状外观扭曲,呈不规则断裂模式,则定义为活状总形(LRC)。LR是一种影响中青年妇女的良性原发性疾病。另一方面,LRC是一种继发性疾病,是病理性的和永久性的。在LR中,生动的锥体变色是对称的、可逆的和均匀的。在LRC中,生动的锥体变色是不可逆的,并且是断裂的。尽管病理学上的livedoid形式是LCR,但在临床研究中并没有明确区分LR和LRC,通常使用“网状livedo”来描述两者。我们的研究包括2013年1月至2021年5月期间被诊断为网状纤维化的8例患者。我们的一个病人是男性,另一个是女性。年龄25 ~ 70岁,平均45.5±16.7岁。虽然主诉为冷、麻、痛,但所有患者均有明显的审美焦虑。体格检查,所有患者下肢可见紫色渔网样外观。其中6例伴静脉功能不全。由于我们采用的治疗方法,静脉功能不全的情况有所改善。然而,由于我们为宇宙学目的应用血管扩张剂治疗,网状外观没有明显改善。由于类活体血管病变发生数年后有发生神经血管和心血管并发症的风险,因此对这些患者进行监测是很重要的。考虑到在COVID-19大流行期间可能在肺部症状之前发现LR,应进行必要的检测以排除这些病例的COVID-19诊断。
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LIVEDO RETICULARIS: CLINICAL SIGNIFICANCE AND TREATMENT
Livedo reticularis (LR) is a hyperpigmented discoloration of the skin characterized by a violet, reticulated cyanotic pattern, and is more common on the extremities and trunk. LR is in the form of intact circular networks. If the circular reticulated appearance is distorted and shows an irregular fracture pattern, it is defined as livedo racemosa (LRC). LR is a benign, primary disease that affects young and middle-aged women. LRC, on the other hand, is a secondary disease, pathological and permanent. In LR, the vivid cone discoloration is symmetrical, reversible, and uniform. In LRC, the vivid cone discoloration is irreversible, and fractured. Although it has been stated as a concept that the pathological livedoid form is LCR, there is no clear distinction between LR and LRC in clinical studies and generally 'livedo reticularis' is used to describe both. Our study includes eight patients diagnosed with livedo reticularis between January 2013 and May 2021. One of our patients was male and the other was female. Their ages ranged from 25 to 70 years and the mean age was 45.5±16.7 years. Although the main complaints were coldness, numbness and pain, aesthetic anxiety was prominent in all patients. On physical examination, violet-colored fishing net-like appearances were noted on the lower extremities of all patients. It was accompanied by venous insufficiency in six of the patients. As a result of the treatment we applied, there was improvement in venous insufficiency. However, as a result of the vasodilator treatment we applied for cosmological purposes, there was no obvious improvement in the reticulated appearances. Because of the risk of developing neurovascular and cardiovascular complications several years after the onset of livedoid vasculopathy, it is important to monitor these patients. Considering that LR may be seen before pulmonary symptoms during the COVID-19 pandemic period, necessary tests should be performed to rule out the diagnosis of COVID-19 in these cases.
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