皂角水提物抗菌洗手凝胶的研制及评价

Jagtar Singh, Mohit Sharma, Thakur Prava, Ritik Kaundal, Ritika Behl, Suryadev Tripathi
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引用次数: 0

摘要

背景:几十年来,草药和食品因其生物相容性和最小的副作用而受到广泛关注。与此同时,植物性化妆品和洗漱用品因其环保性质和与人体皮肤的相容性而抢占了市场。市面上的肥皂和洗手液都是基于有毒的脂肪酸盐、表面活性剂和香水,它们不仅对皮肤有害,而且对环境也有害。十二烷基硫酸钠是肥皂和洗手液中常用的表面活性剂,会使皮肤干燥和敏感。此外,水在进入水体时受到SLS的污染,使水生生物变得脆弱。因此,在不影响其清洁作用和抗微生物特性的情况下,制定生物相容性的洗手液变得非常重要。本作品探索了一种具有良好清洁作用的抗菌洗手液的配方,以生物相容和环保的方式保持个人卫生。结果:以植物提取物为原料制备的中药洗手凝胶具有较强的抗菌作用(对金黄色葡萄球菌和铜绿假单胞菌的最低抑菌浓度分别为1.4cm和3.7 cm)。结论:用天然皂苷和抗菌提取物代替人工合成表面活性剂的植物性洗手液配方可以有效地用于皮肤,同时减少对环境的毒性负荷。
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Formulation and Evaluation of Anti-Microbial Herbal Hand Wash Gel Containing Aqueous Extract of Sapindus Mukorossi
Background: Herbal medicines and food products have extensively been looked upon for decades due to their biocompatible nature and the least adverse effects. At the same pace, plant-based cosmetics and toiletries are capturing the market due to their eco-friendly nature and compatibility with human skin. The marketed soaps and hand washes are based on toxic fatty acid salts, surfactants, and perfumes that are not only harmful to the skin but to the environment as well. The commonly used surfactant in soaps and hand washes, sodium lauryl sulfate makes the skin dry and sensitive. Moreover, the water getting polluted by SLS when entering the water bodies, makes the aquatic life vulnerable. So, it becomes important to formulate such hand washes that are biocompatible, without compromising their cleansing action and anti-microbial properties. This piece of work explores the formulation of an anti-bacterial hand wash having a good cleansing action to serve the purpose of maintaining personal hygiene in a biocompatible and eco-friendly way. Results: Herbal hand wash gel was prepared and evaluated using plant extracts, having potent anti-microbial action (minimum inhibitory concentration of 1.4cm and 3.7 cm for S. aureus and P.aeruginosa respectively). Conclusion: Formulation of plant based hand wash products by replacing the synthetic surfactants with natural saponins and antimicrobial extracts can be useful for regular use on skin, while reducing the toxic load on environment as well.
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