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摘要

在绝大多数心血管疾病(cvd)中,女性和男性在流行病学、病理生理学、临床表现、治疗效果和结局方面存在明显差异。这些差异一方面来自于女性和男性之间的生物学差异,这被称为性别差异,这是由于性染色体基因表达的差异以及随后性激素的差异导致了CV系统中基因表达和功能的差异。相反,性别差异是人类所独有的。它们产生于社会文化进程,例如男女的不同行为;暴露于环境的特定影响;不同形式的营养、生活方式或压力;或者对治疗和预防的态度。科学协会在实施研究和医疗保健策略方面的知识方面处于最前沿,对以女性为中心的方法采取更积极的态度,可能会导致在女性心血管疾病预防和治疗中更具体和有效地利用资源。
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El corazón de la mujer
In the vast majority of cardiovascular diseases (CVDs), there are well-described differences between women and men in epidemiology, pathophysiology, clinical manifestations, effects of therapy, and outcomes. These differences arise on one hand from biological differences among women and men, which are called sex differences, due to differences in gene expression from the sex chromosomes and subsequent differences in sexual hormones leading to differences in gene expression and function in the CV system, In contrast, gender differences are unique to the human. They arise from sociocultural processes, such as different behaviours of women and men; exposure to specific influences of the environment; different forms of nutrition, lifestyle, or stress; or attitudes towards treatments and prevention. The scientific societies are at the forefront of implementing the knowledge in research and healthcare strategies with more proactive attitude for a feminine centered approaches may lead to a more specific and effective use of resources in CVD prevention and therapy in women.
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