肺癌四维计算机断层扫描内部肿瘤靶体积预测模型的可行性

U. Puangragsa, Pitchayakorn Lomvisai, P. Phasukkit, Sarut Puangragsa, J. Setakornnukul, Nongluck Houngkamhang, Petchanon Thongserm, P. Dankulchai
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引用次数: 0

摘要

四维计算机断层扫描(4DCT)是确定呼吸运动引起的器官运动的最常用技术。然而,4DCT获取CT图像的能力作为呼吸期的函数增加了更高的辐射剂量。为了减少患者的辐射剂量,本研究创建了肺运动预测模型,用于通过Kinect在没有辐射的情况下仅检测完整呼吸周期中的外部器官运动来估计十个呼吸期的肿瘤目标运动。在幻像实验中,RPM和Kinect信号的平均总振幅差为0.02±0.1 mm。除2、3、6、7、8类中呼吸方式不规则者的F1评分为85%、83%、90%、84%、85%外,其余大部分分类均为100%。从本质上讲,所提出的肿瘤运动方案的总准确率(F1评分的平均值)为92.7%。深度学习模型可以通过检测外部呼吸信号来预测肿瘤的运动范围和分类区域
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Feasibility of Prediction Model for Internal Tumor Target Volume from 4-D Computed Tomography of Lung cancer
4-Dimensional computed tomography (4DCT) is the most common technique to determine organ movement due to breathing motion. However, the ability of 4DCT to acquire CT images as a function of the respiratory phase increases higher radiation dose. To reduce the patient’s radiation dose, this study created lung motion prediction models used to estimate tumor target movement in ten respiratory phases by detecting only external organ movement during a complete respiration cycle without radiation with Kinect. The average overall amplitude difference between RPM and Kinect signals in the phantom experiment was 0.02 ± 0.1 mm. F1 score of 100% for all most all classifications except classification 2,3,6,7 and 8 of 85%,83%,90%, 84%,85% where irregular breathing pattern. Essentially, the proposed tumor movement scheme’s total accuracy (average of F1 scores) is 92.7 %. Deep learning model can predict tumor motion range and classification zone by used detection of the external respiratory signal
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