衰老的实验病理学。

B Tuchweber, M Salas
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引用次数: 0

摘要

在本综述的第一部分中,我们关注的是那些与衰老过程有关的疾病,或者看起来是这样的疾病。其中一些疾病(如心血管病、肺病、肿瘤)导致大量动物死亡,而另一些疾病(如骨质疏松症、淀粉样变性)虽然明显随着年龄的增长而进展,但并不致命。许多不同的因素影响着正常的衰老过程。限制饮食中的热量摄入可以延长寿命,降低与衰老有关的疾病的发病率和严重程度,这可能是通过抑制脑垂体前叶的功能实现的。
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Experimental pathology of aging.

We have been concerned in the first section of this review with those diseases that are aging processes, or appear to be so. Some of these (e.g., cardiovascular, pulmonary, neoplasia) cause the death of a large proportion of animals, while others (e.g., osteoporosis, amyloidosis), though clearly progressive with age, are nonfatal. Many diverse factors influence the normal process of aging. Restriction of dietary caloric intake prolongs lifespan and decreases the incidence and severity of diseases associated with aging, probably by depressing anterior pituitary gland function...

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