消除菠萝提取物(Ananas comosus L. Merr)对温和姜类硫化物中中性粒细胞的减少的影响

Raissa Febrina, Almurdi Almurdi, Kosno Suprianto
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摘要

牙龈炎的定义是由牙菌斑堆积引起的牙龈炎症。牙菌斑中的细菌释放毒素,促使中性粒细胞向牙龈沟移动,作为主要的保护。用机械或化学方法控制菌斑将是预防和护理牙龈炎的有效方法。化学防治是通过漱口水来完成的。菠萝提取物(Ananas comosus L.merr)含有菠萝蛋白酶,具有抗菌和抗炎的特点。本研究旨在探讨菠萝提取物漱口水对轻度牙龈炎患者龈沟液中性粒细胞计数下降的影响。本研究采用前测与后测相结合的准实验设计,对21例轻度牙龈炎患者,用纸点30吸龈沟液30秒。显微镜下进行中性粒细胞计数。配对t检验分析显示,干预前后中性粒细胞计数显著降低(p<0.05)。用50%菠萝萃取液漱口4天,可减少轻度牙龈炎患者龈沟液中的中性粒细胞计数。
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ENGARUH PENGGUNAAN LARUTAN KUMUR EKSTRAK BUAH NANAS (Ananas comosus L. Merr) TERHADAP PENURUNAN JUMLAH NEUTROFIL DALAM CAIRAN SULKUS GINGIVA PADA PENDERITA GINGIVITIS RINGAN
Gingivitis is defined as gingival inflammation caused by dental plaque accumulation. Bacteria in the plaque is releasing toxin that would trigger neutrophil to move to gingival sulcus as a main protection. Plaque control mechanically or chemically will be an effective prevention and care for gingivitis. Chemical control is done by mouthwash. Pineapple extract (Ananas comosus L.merr) contains bromelain which has antibacterial and antiinflammation features. The aim of this study was to find the effect of using pineapple-extracted mouthwash (Ananas comosus L. Merr) toward neutrophil count drop in gingival crevicular fluid of mild gingivitis patients. This study was quasy experimental using pre-test and post-test design, conducted to 21 patients having mild gingivitis with gingival crevicular fluid were taken by paperpoint 30 for 30 seconds. The neutrophil count was done with microscope. Paired T-test analysis showed that there was significant reduction of neutrophil count before and after the intervention (p<0.05). Mouthwash using 50 % pineapple-extracted solution for four days was proven to reduce neutrophil count in gingival crevicular fluid of mild gingivitis patients.
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