生物组织高脉冲电流实验防腐液适用性测试

N. Bacci, P. Randolph-Quinney, H. Hunt, K. Nixon, T. Augustine
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引用次数: 0

摘要

基于实验室的实际实验表明,高脉冲电流诱导尸体骨骼的微创伤,其模式可能在雷击死亡率测定中有用。然而,尚不清楚用于替代身体体液和保存尸体组织的防腐溶液是否会干扰电流转移和诱导的微创伤模式。因此,测试防腐液的电阻和脉冲电流通过对于建立生物学研究的结构效度至关重要。低压和高压脉冲电流分别应用于等渗盐水、旧的和新鲜的防腐溶液。尽管防腐液具有更大的电流阻力,但所有解决方案的分流电压均持续增加。高压测试表明流体击穿和电流通过所有溶液。通过防腐液的电流传递结果表明,高脉冲电流的大小足以允许在实验中使用防腐组织。
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Testing embalming solution suitability for high impulse current experimentation on biological tissue
Actualistic laboratory-based experimentation has shown that high impulse currents induce microtrauma to cadaveric bone, the patterns of which may have utility in lightning fatality determination However, it is unclear whether embalming solutions used to replace bodily $\mathbf{fluids}$ and preserve the cadaveric tissues, may interfere with current transfer and induced-microtrauma patterns. As such, testing the resistance and impulse current passage of embalming fluids is crucial to build construct validity for biological studies. Low and high voltage impulse currents were applied to isotonic saline, used and fresh embalming solutions. Shunt voltage consistently increased across all solutions, despite embalming fluid having greater resistance to current flow. High voltage tests demonstrated fluid breakdown and current passage throughout all solutions. Current transfer results through embalming fluids suggest that high impulse currents are of sufficient magnitude to allow use of embalmed tissues in experimentation.
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