大黄(Rheum emodi)的植物化学成分及抗氧化活性

A. Shahwan, Naema El Aali, Yusra Layas, Salem G. El Tumi
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引用次数: 3

摘要

药用植物有不同的天然产物和几种抗氧化剂。抗氧化剂在防止氧化应激(OS)造成的破坏方面发挥着主要作用,大黄也不例外,据报道,大黄中含有具有抗氧化活性的化合物,如多酚类化合物。除此之外,其他化合物已被证明具有抗糖尿病、抗菌、抗真菌、细胞毒性、肝保护和肾保护活性。本研究旨在定量研究红曲粉末状植物的水提取物,以评价其清除自由基的能力。测定了总酚、总黄酮含量和还原能力,以考虑未来植物中新型抗氧化剂的可能来源。TPC、TFC和还原力随菌株浓度的增加而增加。在1000µg/ml时,TPC的吸光度为1.437,TFC的吸光度为1.602,还原功率法的吸光度为1.638,均大于相同浓度下的标准品。提取的还原力、酚类和类黄酮含量高于标准邻苯三酚、槲皮素和抗坏血酸。
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Phytochemical content and antioxidant activities of Rhubarb (Rheum emodi)
Medicinal plants have varying natural products and several antioxidants. Antioxidants play a principal function to protect against destruction caused by oxidative stress (OS), Rheum emodi is not an exception, in which it is reported to have compounds that possess antioxidant activity, like polyphenolic compounds. In addition to that, other compounds have proven to have antidiabetic, antimicrobial, antifungal, cytotoxic, hepatoprotective, and nephroprotective activities. This study aimed to quantify the water extract of a powdered plant of R. emodi to evaluate its ability to scavage free radicals. Total phenolic, total flavonoid contents, and reducing ability were measured to consider possible sources of future novel antioxidants in plants. The TPC, TFC, and reducing power assay increased with increasing concentrations of R. emodi. At 1000 µg/ml, the absorbance ranged from 1.437 for TPC, 1.602 for TFC, and 1.638 for reducing power assay, which is more than the absorbance of the standards at the same concentration. The extracted content of reducing power, phenolic, and flavonoid compounds were higher than the standard pyrogallol, quercetin, and ascorbic acid.
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