在海拔舱中攀爬到5000米高度时人体适应机制的差异

L. Bragin, A. Goncharova, D.L. Bragin, A. M. Nosovsky
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摘要

尽管人体在缺氧条件下的行为已经得到了充分的研究,但仍有许多问题需要进一步研究。识别和分类身体对特定环境条件变化的典型反应,主要与极端职业框架内的活动表现有关,仍然是实际问题。本研究的目的是确定不同背景值的个体在暴露于高海拔缺氧条件下,心血管系统主要指标——血压(BP)、心率(HR)和呼吸频率(RR)状态的变化。在对43名30-35岁的健康男性志愿者进行研究后(按照原方法将受试者在压力室中升高到5000 m高度),发现受试者的BP、RR和HR随背景值的变化呈现出不同的“模式”。BP与其背景值成比例增加。RR的变化具有复杂的动态。背景指标值不同的个体,其HR增加到基本相同的值。在选择个体进行与高原缺氧条件相关的活动时,应考虑BP、RR和HR的变化模式。这些模式还将使已经从事这类活动的人能够根据其身体的生理特征,优化其工作和休息时间。
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The difference between the adaptive mechanisms of the human body when climbing to a height of 5000 m in the altitude chamber
Despite the fact that the behavior of the human body when exposed to hypoxia has been sufficiently studied, a number of issues need further study. Identification and classification of the body's typical reactions to specific changes in environmental conditions, primarily related to the performance of activities within the framework of extreme professions, remain the actual problem. The objective of the study was to identify changes in the state of the main indicators of the cardiovascular system – blood pressure (BP), heart rate (HR) and respiratory rate (RR) – in individuals with different background values of these indicators when exposed to conditions of high-altitude hypoxia. After the study of 43 healthy male volunteers aged 30–35 (conducted according to the original method of raising the subjects in the pressure chamber to a height of 5000 m) it was found the subjects showed different "patterns" of changes in BP, RR and HR, depending on the background values. BP increased in proportion to its background values. The change in RR had a complex dynamics. And the HR increased to approximately the same values in individuals with different values of background indicators. The revealed patterns of changes in BP, RR and HR should be taken into account when selecting individuals for activities associated with being in conditions of high-altitude hypoxia. The patterns will also make it possible to optimize the work and rest time of persons already engaged in such activities, depending on the physiological characteristics of their body.
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