基于语言节奏相关特征的帕金森病严重程度自动估计

Dávid Sztahó, Miklós Gábriel Tulics, K. Vicsi, I. Valálik
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引用次数: 12

摘要

帕金森氏症等疾病会损害患者的认知过程,从而影响言语。在本文中,我们提出了一种基于匈牙利帕金森患者和健康对照人群的运行语音(阅读文本和独白)中提取的语音节奏相关特征的帕金森病严重程度估计方法。分类和回归模型分别使用不同的机器学习方法为两种语言类型建立。对不同的文本类型分别作出或共同作出决定。最后通过对每个说话人的独立估计进行融合得到预测结果。测试试验是为了调查年龄是否是机器学习任务的相关特征。研究发现,基于分类和回归性能,所研究的特征对帕金森病的自动诊断是有用的和高度相关的。使用支持向量机(和回归)获得最佳结果,二元分类准确率为84.62%,Hoehn-Yahr量表帕金森严重程度估计的Spearman相关系数为0.735。
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Automatic estimation of severity of Parkinson's disease based on speech rhythm related features
Diseases, such as Parkinson, impairs cognitive processes of patients, through which speech is also affected. In this paper, we propose a method for Parkinson's disease severity level estimation based on speech rhythm related features extracted from running speech (read texts and monologue) uttered by Hungarian Parkinson patients and healthy control population. Classification and regression models are built using various machine-learning methods for both linguistic types separately. Separate and joint decisions were made for the different text types. The final prediction was obtained by fusing the separate estimations for each speaker. Test trials were run in order to investigate, if age is a relevant feature for the machine learning tasks. It was found that the investigated features are useful and highly relevant for the automatic diagnosis of Parkinson's disease based on the classification and regression performances. The best results were obtained using support vector machine (and regression) with 84.62% accuracy for binary classification and 0.735 Spearman correlation for Parkinson severity level estimation measured on the Hoehn-Yahr scale.
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